ENSDARG00000006207


Danio rerio

Features
Gene ID: ENSDARG00000006207
  
Biological name :gpx1b
  
Synonyms : glutathione peroxidase 1b / gpx1b
  
Possible biological names infered from orthology : glutathione peroxidase 2 / GPX2 / P18283
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 42338309
Gene end: 42341219
  
Corresponding Affymetrix probe sets: Dr.8000.1.S1_at (Zebrafish Array)   NM_001004634_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000011398
NCBI entrez gene - 447895     See in Manteia.
RefSeq - NM_001004634
RefSeq Peptide - NP_001004634
swissprot - Q66IE1
ZFIN ID - ZDB-GENE-040912-60
Ensembl - ENSDARG00000006207
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GPX2ENSGALG00000042031Gallus gallus
 GPX2ENSG00000176153Homo sapiens
 Gpx2ENSMUSG00000042808Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gpx1a / glutathione peroxidase 1a / GPX2* / P18283* / glutathione peroxidase 2*ENSDARG0000001814679
gpx3 / glutathione peroxidase 3 / GPX6* / GPX5* / P46412* / Q91WR8* / P59796* / O75715* / P21765* / P22352* / glutathione peroxidase 6* / glutathione peroxidase 5* / Epididymal secretory gl...ENSDARG0000004334246
si:ch73-111m19.2ENSDARG0000000307743
gpx4b / glutathione peroxidase 4b / GPX4* / P36969* / glutathione peroxidase 4*ENSDARG0000007683634
gpx4a / glutathione peroxidase 4aENSDARG0000006847833
gpx7 / glutathione peroxidase 7 / Q96SL4*ENSDARG0000009151124
gpx8 / glutathione peroxidase 8 (putative) / Q8TED1*ENSDARG0000001330222


Protein motifs (from Interpro)
Interpro ID Name
 IPR000889  Glutathione peroxidase
 IPR012336  Thioredoxin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004601 peroxidase activity IEA
 molecular_functionGO:0004602 glutathione peroxidase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of 12-eicosatetraenoic acid derivatives
Detoxification of Reactive Oxygen Species
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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