ENSDARG00000006691


Danio rerio

Features
Gene ID: ENSDARG00000006691
  
Biological name :rpl12
  
Synonyms : ribosomal protein L12 / rpl12
  
Possible biological names infered from orthology : Gm16519 / P30050 / P35979
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 32882688
Gene end: 32887020
  
Corresponding Affymetrix probe sets: Dr.24686.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000009096
Ensembl peptide - ENSDARP00000150760
swissprot - Q6DRE6
ZFIN ID - ZDB-GENE-030131-5297
Ensembl - ENSDARG00000006691
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPL12ENSGALG00000008806Gallus gallus
 RPL12ENSG00000197958Homo sapiens
 Gm16519ENSMUSG00000066983Mus musculus
 Rpl12ENSMUSG00000038900Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000911  Ribosomal protein L11/L12
 IPR020783  Ribosomal protein L11, C-terminal
 IPR020784  Ribosomal protein L11, N-terminal
 IPR020785  Ribosomal protein L11, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000027 ribosomal large subunit assembly IBA
 biological_processGO:0006412 translation IBA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit IBA
 molecular_functionGO:0003735 structural constituent of ribosome IBA
 molecular_functionGO:0019843 rRNA binding IBA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
SRP-dependent cotranslational protein targeting to membrane
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000029 hindbrain hindbrain quality , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary condensed , abnormal
midbrain hindbrain boundary quality , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000084 yolk yolk circular , abnormal
yolk grey , abnormal
yolk quality , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle distended , abnormal
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 ZFA:0000112 gut gut hypoplastic , abnormal
gut quality , abnormal
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 ZFA:0000123 liver liver hypoplastic , abnormal
liver quality , abnormal
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 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0000598 testis testis seminoma present , abnormal
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 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism Lymphoid neoplasms neoplastic, malignant , abnormal
whole organism shape , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk decreased thickness , abnormal
trunk atrophied , abnormal
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 ZFA:0001439 anatomical system anatomical system quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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