ENSDARG00000007081


Danio rerio

Features
Gene ID: ENSDARG00000007081
  
Biological name :pias4a
  
Synonyms : pias4a / protein inhibitor of activated STAT, 4a
  
Possible biological names infered from orthology : PIAS4 / protein inhibitor of activated STAT 4 / Q8N2W9 / Q9JM05
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 20406410
Gene end: 20419660
  
Corresponding Affymetrix probe sets: Dr.20913.1.S1_at (Zebrafish Array)   Dr.5265.1.A1_at (Zebrafish Array)   Dr.6651.1.A1_at (Zebrafish Array)   Dr.6651.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000096293
swissprot - F1R4C4
ZFIN ID - ZDB-GENE-040426-2734
Ensembl - ENSDARG00000007081
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PIAS4ENSGALG00000034413Gallus gallus
 PIAS4ENSG00000105229Homo sapiens
 Pias4ENSMUSG00000004934Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pias1b / protein inhibitor of activated STAT, 1b / PIAS1* / O88907* / O75925* / protein inhibitor of activated STAT 1*ENSDARG0000006244541
pias4b / protein inhibitor of activated STAT, 4b / PIAS4* / Q9JM05* / Q8N2W9* / protein inhibitor of activated STAT 4*ENSDARG0000004221541
pias1a / protein inhibitor of activated STAT, 1a / PIAS1* / O88907* / O75925* / protein inhibitor of activated STAT 1*ENSDARG0000003609440
pias2 / protein inhibitor of activated STAT, 2 / O75928* / Q8C5D8* / E3 SUMO-protein ligase PIAS2 *ENSDARG0000009297937
zmiz2 / zinc finger, MIZ-type containing 2 / Q8CIE2* / Q8NF64*ENSDARG0000009868320
zmiz1a / zinc finger, MIZ-type containing 1a / ZMIZ1* / Q6P1E1* / Q9ULJ6* / zinc finger MIZ-type containing 1*ENSDARG0000007450220
zmiz1b / zinc finger, MIZ-type containing 1b / ZMIZ1* / Q6P1E1* / Q9ULJ6* / zinc finger MIZ-type containing 1*ENSDARG0000010227918


Protein motifs (from Interpro)
Interpro ID Name
 IPR003034  SAP domain
 IPR004181  Zinc finger, MIZ-type
 IPR023321  PINIT domain
 IPR027224  E3 SUMO-protein ligase PIAS4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016925 protein sumoylation IEA
 biological_processGO:0032480 negative regulation of type I interferon production IMP
 biological_processGO:0060339 negative regulation of type I interferon-mediated signaling pathway IMP
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019789 SUMO transferase activity IEA


Pathways (from Reactome)
Pathway description
Vitamin D (calciferol) metabolism
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of ubiquitinylation proteins
SUMOylation of SUMOylation proteins
SUMOylation of intracellular receptors
SUMOylation of DNA replication proteins
SUMOylation of immune response proteins
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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