ENSDARG00000008029


Danio rerio

Features
Gene ID: ENSDARG00000008029
  
Biological name :mep1a.2
  
Synonyms : mep1a.2 / meprin A, alpha (PABA peptide hydrolase), tandem duplicate 2
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 35484070
Gene end: 35496459
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000009962
Ensembl peptide - ENSDARP00000122457
NCBI entrez gene - 565535     See in Manteia.
RefSeq - NM_001128727
RefSeq Peptide - NP_001122199
swissprot - F1QRQ5
swissprot - B3DKP9
ZFIN ID - ZDB-GENE-041001-208
Ensembl - ENSDARG00000008029
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mep1a.1 / meprin A, alpha (PABA peptide hydrolase), tandem duplicate 1 / MEP1A* / P28825* / Q16819* / meprin A subunit alpha*ENSDARG0000002974749
si:ch73-40a17.3 / MEP1B* / Q16820* / Q61847* / meprin A subunit beta*ENSDARG0000004068341
mep1b / meprin A, beta / Q16820* / Q61847* / meprin A subunit beta*ENSDARG0000003753339
he1.2 / he1.1 / hatching enzyme 1, tandem duplicate 1 / ASTL* / Q6HA09* / Q6HA08* / astacin like metalloendopeptidase*ENSDARG0000002365613
he1.2 / hatching enzyme 1, tandem dupliate 2 / ASTL* / Q6HA08* / Q6HA09* / astacin like metalloendopeptidase*ENSDARG0000001912213
CU326366.2ENSDARG0000006859313
c6ast1 / six-cysteine containing astacin protease 1ENSDARG0000006921612
he1.3 / hatching enzyme 1, tandem duplicate 3 / ASTL* / Q6HA08* / Q6HA09* / astacin like metalloendopeptidase*ENSDARG0000002267012
si:ch211-167j6.4ENSDARG0000007001112
c6ast4 / six-cysteine containing astacin protease 4ENSDARG0000005257812
si:ch211-167j6.5ENSDARG0000005840912
c6ast3 / six-cysteine containing astacin protease 3ENSDARG0000002450311
npsn / nephrosinENSDARG0000001042311


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR000998  MAM domain
 IPR001506  Peptidase M12A
 IPR002083  MATH/TRAF domain
 IPR006026  Peptidase, metallopeptidase
 IPR008294  Meprin alpha/beta subunit
 IPR008974  TRAF-like
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034301  Meprin alpha subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium dilated , abnormal
Show

 ZFA:0001115 trunk trunk epidermis morphology , abnormal
Show

 ZFA:0001117 post-vent region post-vent region epidermis morphology , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel aplastic , abnormal
Show

 ZFA:0005037 post-vent vasculature post-vent vasculature postero-ventral region increased accumulation nucleate erythrocyte , abnormal
Show

 ZFA:0005249 vasculature vasculature degenerate , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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