ENSDARG00000019122


Danio rerio

Features
Gene ID: ENSDARG00000019122
  
Biological name :he1.2
  
Synonyms : hatching enzyme 1, tandem dupliate 2 / he1.2
  
Possible biological names infered from orthology : astacin like metalloendopeptidase / ASTL / Q6HA08 / Q6HA09
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 14098028
Gene end: 14099399
  
Corresponding Affymetrix probe sets: Dr.1691.9.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000009264
NCBI entrez gene - 407971     See in Manteia.
RefSeq - NM_213635
RefSeq Peptide - NP_998800
swissprot - Q1LW01
ZFIN ID - ZDB-GENE-030131-2100
Ensembl - ENSDARG00000019122
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ASTLENSG00000188886Homo sapiens
 AstlENSMUSG00000050468Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
he1.2 / he1.1 / hatching enzyme 1, tandem duplicate 1 / ASTL* / Q6HA09* / Q6HA08* / astacin like metalloendopeptidase*ENSDARG0000002365699
he1.3 / hatching enzyme 1, tandem duplicate 3 / ASTL* / Q6HA08* / Q6HA09* / astacin like metalloendopeptidase*ENSDARG0000002267057
si:ch211-167j6.5ENSDARG0000005840943
si:ch211-167j6.4ENSDARG0000007001140
npsn / nephrosinENSDARG0000001042340
c6ast1 / six-cysteine containing astacin protease 1ENSDARG0000006921640
c6ast4 / six-cysteine containing astacin protease 4ENSDARG0000005257840
c6ast3 / six-cysteine containing astacin protease 3ENSDARG0000002450339
mep1a.2 / meprin A, alpha (PABA peptide hydrolase), tandem duplicate 2ENSDARG0000000802935
mep1b / meprin A, beta / Q16820* / Q61847* / meprin A subunit beta*ENSDARG0000003753333
mep1a.1 / meprin A, alpha (PABA peptide hydrolase), tandem duplicate 1 / MEP1A* / P28825* / Q16819* / meprin A subunit alpha*ENSDARG0000002974733
si:ch73-40a17.3 / MEP1B* / Q16820* / Q61847* / meprin A subunit beta*ENSDARG0000004068333
CU326366.2ENSDARG0000006859327


Protein motifs (from Interpro)
Interpro ID Name
 IPR001506  Peptidase M12A
 IPR006026  Peptidase, metallopeptidase
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034039  Hatching enzyme, peptidase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IDA
 biological_processGO:0035188 hatching IDA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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