ENSDARG00000008322


Danio rerio

Features
Gene ID: ENSDARG00000008322
  
Biological name :ambra1a
  
Synonyms : ambra1a / autophagy/beclin-1 regulator 1a
  
Possible biological names infered from orthology : A2AH22 / Activating molecule in BECN1-regulated autophagy protein 1 / AMBRA1 / autophagy and beclin 1 regulator 1 / Q9C0C7
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 39255781
Gene end: 39360325
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000142964
Ensembl peptide - ENSDARP00000151820
Ensembl peptide - ENSDARP00000151646
Ensembl peptide - ENSDARP00000088806
NCBI entrez gene - 100332642     See in Manteia.
RefSeq - NM_001281992
RefSeq Peptide - NP_001268921
swissprot - L0N9D3
swissprot - E7FAG6
swissprot - L0N9D4
swissprot - A0A1D5NSZ3
ZFIN ID - ZDB-GENE-111104-2
Ensembl - ENSDARG00000008322
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AMBRA1ENSGALG00000008358Gallus gallus
 AMBRA1ENSG00000110497Homo sapiens
 A2AH22ENSMUSG00000040506Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ambra1b / autophagy/beclin-1 regulator 1b / A2AH22* / AMBRA1* / Q9C0C7* / autophagy and beclin 1 regulator 1* / Activating molecule in BECN1-regulated autophagy protein 1 *ENSDARG0000003987855


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006914 autophagy IBA
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0048741 skeletal muscle fiber development IMP
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000088 YSL YSL edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye adjacent to eye , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle hydrocephalic , abnormal
Show

 ZFA:0000135 notochord notochord undulate , abnormal
notochord disorganized , abnormal
Show

 ZFA:0000155 somite somite morphology , abnormal
somite shape , abnormal
Show

 ZFA:0000159 tectal ventricle tectal ventricle hydrocephalic , abnormal
Show

 ZFA:0000473 trunk musculature trunk musculature muscle cell disorganized , abnormal
Show

 ZFA:0001089 myoseptum myoseptum morphology , abnormal
myoseptum unstructured , abnormal
myoseptum decreased thickness , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis shortened , abnormal
whole organism deformed , abnormal
whole organism decreased size , abnormal
whole organism refractivity , abnormal
whole organism dead , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head apoptotic , abnormal
Show

 ZFA:0001115 trunk trunk decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region kinked , abnormal
post-vent region deformed , abnormal
post-vent region curved , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , abnormal
Show

 ZFA:0001617 otolith otolith decreased size , abnormal
Show

 ZFA:0005035 subintestinal vein subintestinal vein morphology , abnormal
Show

 ZFA:0005145 muscle muscle disorganized , abnormal
muscle mitochondrion morphology , abnormal
muscle striated muscle thin filament separated from muscle myosin filament, abnormal
muscle sarcoplasmic reticulum dilated , abnormal
muscle sarcomere disorganized , abnormal
muscle sarcomere decreased amount , abnormal
Show

 ZFA:0009114 muscle cell muscle cell degenerate , abnormal
muscle cell disorganized , abnormal
muscle cell nucleus morphology , abnormal
muscle cell nucleus increased amount , abnormal
Show

 ZFA:0009117 fast muscle cell fast muscle cell undulate , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr