ENSDARG00000009160


Danio rerio

Features
Gene ID: ENSDARG00000009160
  
Biological name :kmo
  
Synonyms : kmo / kynurenine 3-monooxygenase
  
Possible biological names infered from orthology : O15229 / Q91WN4
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 42272515
Gene end: 42306348
  
Corresponding Affymetrix probe sets: Dr.24719.1.S1_at (Zebrafish Array)   Dr.24719.1.S1_x_at (Zebrafish Array)   Dr.24719.2.A1_at (Zebrafish Array)   NM_001040306_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000024051
NCBI entrez gene - 101885014     See in Manteia.
NCBI entrez gene - 368242     See in Manteia.
RefSeq - NM_001040306
RefSeq - NM_001327824
RefSeq Peptide - NP_001035396
RefSeq Peptide - NP_001314753
swissprot - F1QHH6
ZFIN ID - ZDB-GENE-030424-4
Ensembl - ENSDARG00000009160
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KMOENSGALG00000007503Gallus gallus
 KMOENSG00000117009Homo sapiens
 KmoENSMUSG00000039783Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002938  FAD-binding domain
 IPR023753  FAD/NAD(P)-binding domain
 IPR027545  Kynurenine 3-monooxygenase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006569 tryptophan catabolic process IEA
 biological_processGO:0009435 NAD biosynthetic process IEA
 biological_processGO:0019363 pyridine nucleotide biosynthetic process IEA
 biological_processGO:0019805 quinolinate biosynthetic process IEA
 biological_processGO:0034354 "de novo" NAD biosynthetic process from tryptophan IEA
 biological_processGO:0043420 anthranilate metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004502 kynurenine 3-monooxygenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0071949 FAD binding IEA


Pathways (from Reactome)
Pathway description
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000088 YSL YSL edematous , abnormal
Show

 ZFA:0005285 glomerular basement membrane glomerular basement membrane decreased functionality , abnormal
Show

 ZFA:0009285 podocyte podocyte podocyte foot morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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