ENSG00000117009


Homo sapiens

Features
Gene ID: ENSG00000117009
  
Biological name :KMO
  
Synonyms : KMO / kynurenine 3-monooxygenase / O15229
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q43
Gene start: 241532134
Gene end: 241595642
  
Corresponding Affymetrix probe sets: 205306_x_at (Human Genome U133 Plus 2.0 Array)   205307_s_at (Human Genome U133 Plus 2.0 Array)   211138_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355513
Ensembl peptide - ENSP00000355515
Ensembl peptide - ENSP00000355516
Ensembl peptide - ENSP00000355517
NCBI entrez gene - 8564     See in Manteia.
OMIM - 603538
RefSeq - XM_017002650
RefSeq - NM_003679
RefSeq - XM_005273337
RefSeq - XM_005273338
RefSeq - XM_017002649
RefSeq Peptide - NP_003670
swissprot - O15229
swissprot - H0Y320
Ensembl - ENSG00000117009
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kmoENSDARG00000009160Danio rerio
 KMOENSGALG00000007503Gallus gallus
 KmoENSMUSG00000039783Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002938  FAD-binding domain
 IPR027545  Kynurenine 3-monooxygenase
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006569 tryptophan catabolic process TAS
 biological_processGO:0009435 NAD biosynthetic process IEA
 biological_processGO:0009651 response to salt stress IDA
 biological_processGO:0019363 pyridine nucleotide biosynthetic process IEA
 biological_processGO:0019441 tryptophan catabolic process to kynurenine IEA
 biological_processGO:0019674 NAD metabolic process IBA
 biological_processGO:0019805 quinolinate biosynthetic process IEA
 biological_processGO:0044550 secondary metabolite biosynthetic process IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070189 kynurenine metabolic process IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane ISS
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004502 kynurenine 3-monooxygenase activity TAS
 molecular_functionGO:0016174 NAD(P)H oxidase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IDA
 molecular_functionGO:0071949 FAD binding IEA


Pathways (from Reactome)
Pathway description
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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