ENSDARG00000009779


Danio rerio

Features
Gene ID: ENSDARG00000009779
  
Biological name :mcl1a
  
Synonyms : mcl1a / MCL1, BCL2 family apoptosis regulator a
  
Possible biological names infered from orthology : Induced myeloid leukemia cell differentiation / MCL1 / MCL1, BCL2 family apoptosis regulator / P97287 / Q07820
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 348729
Gene end: 353231
  
Corresponding Affymetrix probe sets: Dr.4957.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000098601
swissprot - Q1L8X3
ZFIN ID - ZDB-GENE-000511-7
Ensembl - ENSDARG00000009779
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MCL1ENSGALG00000044383Gallus gallus
 MCL1ENSG00000143384Homo sapiens
 Mcl1ENSMUSG00000038612Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mcl1b / MCL1, BCL2 family apoptosis regulator b / MCL1* / Q07820* / P97287* / MCL1, BCL2 family apoptosis regulator* / Induced myeloid leukemia cell differentiation *ENSDARG0000000836335
bcl2l10 / BCL2 like 10ENSDARG0000002676615


Protein motifs (from Interpro)
Interpro ID Name
 IPR002475  Bcl2-like
 IPR013281  Apoptosis regulator, Mcl-1
 IPR026298  Blc2 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001894 tissue homeostasis IMP
 biological_processGO:0007088 regulation of mitotic nuclear division IGI
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0042981 regulation of apoptotic process IGI
 biological_processGO:0043009 chordate embryonic development IGI
 biological_processGO:0043066 negative regulation of apoptotic process IGI
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0045839 negative regulation of mitotic nuclear division IGI
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IBA
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IBA
 cellular_componentGO:0005741 mitochondrial outer membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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