ENSDARG00000010160


Danio rerio

Features
Gene ID: ENSDARG00000010160
  
Biological name :rps15a
  
Synonyms : ribosomal protein S15a / rps15a
  
Possible biological names infered from orthology : 40S ribosomal protein S15a / P62244 / P62245
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 26345732
Gene end: 26351656
  
Corresponding Affymetrix probe sets: Dr.1428.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000108197
Ensembl peptide - ENSDARP00000134460
NCBI entrez gene - 336764     See in Manteia.
swissprot - Q6Q420
ZFIN ID - ZDB-GENE-030131-8708
Ensembl - ENSDARG00000010160
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPS15AENSGALG00000006771Gallus gallus
 P62244ENSG00000134419Homo sapiens
 P62245ENSMUSG00000008683Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arl6ip1 / ADP-ribosylation factor-like 6 interacting protein 1ENSDARG0000005457814


Protein motifs (from Interpro)
Interpro ID Name
 IPR000630  Ribosomal protein S8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0051726 regulation of cell cycle IMP
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit IBA
 molecular_functionGO:0003735 structural constituent of ribosome IBA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
SRP-dependent cotranslational protein targeting to membrane
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000006 ball ball increased size , abnormal
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 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000029 hindbrain hindbrain opaque , abnormal
hindbrain undulate , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary aplastic , abnormal
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 ZFA:0000079 telencephalon telencephalon decreased size , abnormal
telencephalon deformed , abnormal
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 ZFA:0000084 yolk yolk circular , abnormal
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 ZFA:0000100 cerebellum cerebellum decreased thickness , abnormal
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 ZFA:0000106 extension extension decreased length , abnormal
extension decreased thickness , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000108 fin fin aplastic , abnormal
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 ZFA:0000109 forebrain forebrain protruding , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle opaque , abnormal
fourth ventricle distended , abnormal
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 ZFA:0000138 otic placode otic placode aplastic , abnormal
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 ZFA:0000142 peripheral nervous system peripheral nervous system nerve neoplastic , abnormal
peripheral nervous system chromosome amount , abnormal
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 ZFA:0000152 retina retina decreased size , abnormal
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 ZFA:0000160 tegmentum tegmentum opaque , abnormal
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 ZFA:0000445 optic tectum optic tectum increased size , abnormal
optic tectum opaque , abnormal
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 ZFA:0001094 whole organism whole organism quality , abnormal
whole organism decreased size , abnormal
whole organism viability , abnormal
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 ZFA:0001114 head head flat , abnormal
head decreased size , abnormal
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 ZFA:0001115 trunk trunk curved , abnormal
trunk decreased thickness , abnormal
trunk degenerate , abnormal
trunk bent , abnormal
trunk curved ventral , abnormal
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 ZFA:0001117 post-vent region post-vent region bent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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