ENSDARG00000010477


Danio rerio

Features
Gene ID: ENSDARG00000010477
  
Biological name :p2rx3a
  
Synonyms : p2rx3a / purinergic receptor P2X, ligand-gated ion channel, 3a
  
Possible biological names infered from orthology : P2RX3 / P2X purinoceptor 3 / P56373 / purinergic receptor P2X 3 / Q3UR32
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 21942383
Gene end: 21959712
  
Corresponding Affymetrix probe sets: Dr.8239.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000019781
swissprot - B3DG55
ZFIN ID - ZDB-GENE-000427-3
Ensembl - ENSDARG00000010477
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P2RX3ENSGALG00000040479Gallus gallus
 P2RX3ENSG00000109991Homo sapiens
 P2rx3ENSMUSG00000027071Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
p2rx3b / purinergic receptor P2X, ligand-gated ion channel, 3b / P2RX3* / Q3UR32* / P56373* / P2X purinoceptor 3 * / purinergic receptor P2X 3*ENSDARG0000002971859
p2rx5 / purinergic receptor P2X, ligand-gated ion channel, 5 / Q93086* / P2RX5-TAX1BP3* / purinergic receptor P2X 5* / P2RX5-TAX1BP3 readthrough (NMD candidate)*ENSDARG0000000445539
p2rx1 / purinergic receptor P2X, ligand-gated ion channel, 1 / P51575* / P51576* / P2X purinoceptor 1 * / purinergic receptor P2X 1*ENSDARG0000001669539
p2rx4a / purinergic receptor P2X, ligand-gated ion channel, 4a / P2RX4* / Q99571* / purinergic receptor P2X 4*ENSDARG0000004475237
p2rx4b / purinergic receptor P2X, ligand-gated ion channel, 4b / P2RX4* / Q99571* / purinergic receptor P2X 4*ENSDARG0000004245237
p2rx2 / purinergic receptor P2X, ligand-gated ion channel, 2 / Q9UBL9* / Q8K3P1* / P2X purinoceptor 2 * / purinergic receptor P2X 2*ENSDARG0000000230037
p2rx8 / purinergic receptor P2X, ligand-gated ion channel, 8 / P2RX5* / Q93086* / P2RX5-TAX1BP3* / purinergic receptor P2X 5* / P2RX5-TAX1BP3 readthrough (NMD candidate)* / purinergic recep...ENSDARG0000002413933
p2rx7 / purinergic receptor P2X, ligand-gated ion channel, 7 / Q9Z1M0* / Q99572* / P2X purinoceptor 7 * / purinergic receptor P2X 7*ENSDARG0000004244032


Protein motifs (from Interpro)
Interpro ID Name
 IPR001429  P2X purinoreceptor
 IPR003046  P2X3 purinoceptor
 IPR027309  P2X purinoreceptor extracellular domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IGI
 biological_processGO:0022008 neurogenesis IMP
 biological_processGO:0033198 response to ATP IEA
 biological_processGO:0035590 purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0051291 protein heterooligomerization IGI
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005639 integral component of nuclear inner membrane IBA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0001614 purinergic nucleotide receptor activity IBA
 molecular_functionGO:0004931 extracellularly ATP-gated cation channel activity IGI
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Elevation of cytosolic Ca2+ levels
Platelet homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000295 trigeminal ganglion trigeminal ganglion malformed , abnormal
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 ZFA:0001273 ventral mandibular arch ventral mandibular arch malformed , abnormal
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 ZFA:0001306 pharyngeal arch pharyngeal arch malformed , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
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 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage hypotrophic , abnormal
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 ZFA:0001555 epibranchial ganglion epibranchial ganglion malformed , abnormal
Show

 ZFA:0001611 pharyngeal arch 2 pharyngeal arch 2 morphology , abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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