ENSDARG00000042452


Danio rerio

Features
Gene ID: ENSDARG00000042452
  
Biological name :p2rx4b
  
Synonyms : p2rx4b / purinergic receptor P2X, ligand-gated ion channel, 4b
  
Possible biological names infered from orthology : P2RX4 / purinergic receptor P2X 4 / Q99571
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 30743263
Gene end: 30755977
  
Corresponding Affymetrix probe sets: Dr.14988.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000145823
Ensembl peptide - ENSDARP00000089746
NCBI entrez gene - 387301     See in Manteia.
NCBI entrez gene - 415171     See in Manteia.
RefSeq - NM_198987
RefSeq Peptide - NP_945338
swissprot - B0V1H9
ZFIN ID - ZDB-GENE-030319-4
Ensembl - ENSDARG00000042452
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P2RX4ENSGALG00000003901Gallus gallus
 P2RX4ENSG00000135124Homo sapiens
 P2rx4ENSMUSG00000029470Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
p2rx4a / purinergic receptor P2X, ligand-gated ion channel, 4a / P2RX4* / Q99571* / purinergic receptor P2X 4*ENSDARG0000004475256
p2rx7 / purinergic receptor P2X, ligand-gated ion channel, 7 / Q9Z1M0* / Q99572* / P2X purinoceptor 7 * / purinergic receptor P2X 7*ENSDARG0000004244042
p2rx5 / purinergic receptor P2X, ligand-gated ion channel, 5 / Q93086* / P2RX5-TAX1BP3* / purinergic receptor P2X 5* / P2RX5-TAX1BP3 readthrough (NMD candidate)*ENSDARG0000000445542
p2rx2 / purinergic receptor P2X, ligand-gated ion channel, 2 / Q9UBL9* / Q8K3P1* / P2X purinoceptor 2 * / purinergic receptor P2X 2*ENSDARG0000000230040
p2rx1 / purinergic receptor P2X, ligand-gated ion channel, 1 / P51575* / P51576* / P2X purinoceptor 1 * / purinergic receptor P2X 1*ENSDARG0000001669540
p2rx3b / purinergic receptor P2X, ligand-gated ion channel, 3b / P2RX3* / Q3UR32* / P56373* / P2X purinoceptor 3 * / purinergic receptor P2X 3*ENSDARG0000002971840
p2rx3a / purinergic receptor P2X, ligand-gated ion channel, 3a / P2RX3* / Q3UR32* / P56373* / P2X purinoceptor 3 * / purinergic receptor P2X 3*ENSDARG0000001047738
p2rx8 / purinergic receptor P2X, ligand-gated ion channel, 8 / P2RX5* / Q93086* / P2RX5-TAX1BP3* / purinergic receptor P2X 5* / P2RX5-TAX1BP3 readthrough (NMD candidate)* / purinergic recep...ENSDARG0000002413937


Protein motifs (from Interpro)
Interpro ID Name
 IPR001163  LSM domain, eukaryotic/archaea-type
 IPR001429  P2X purinoreceptor
 IPR003045  P2X2 purinoceptor
 IPR010920  LSM domain superfamily
 IPR027141  Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3
 IPR027309  P2X purinoreceptor extracellular domain superfamily
 IPR034099  Small nuclear ribonucleoprotein Sm D3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IDA
 biological_processGO:0033198 response to ATP IEA
 biological_processGO:0035590 purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0001614 purinergic nucleotide receptor activity IEA
 molecular_functionGO:0004931 extracellularly ATP-gated cation channel activity IDA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Elevation of cytosolic Ca2+ levels
Platelet homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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