ENSDARG00000010844


Danio rerio

Features
Gene ID: ENSDARG00000010844
  
Biological name :kras
  
Synonyms : kras / v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 31099908
Gene end: 31118923
  
Corresponding Affymetrix probe sets: Dr.20193.1.A1_at (Zebrafish Array)   Dr.9293.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000021124
Ensembl peptide - ENSDARP00000147703
NCBI entrez gene - 445289     See in Manteia.
RefSeq - XM_009298118
swissprot - Q6AZA4
ZFIN ID - ZDB-GENE-040808-67
Ensembl - ENSDARG00000010844
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hrasa / v-Ha-ras Harvey rat sarcoma viral oncogene homolog a / HRAS* / P01112* / Q61411* / HRas proto-oncogene, GTPase* / GTPase HRas GTPase HRas, N-terminally processed*ENSDARG0000009849785
hrasb / -Ha-ras Harvey rat sarcoma viral oncogene homolog b / HRAS* / P01112* / Q61411* / HRas proto-oncogene, GTPase* / GTPase HRas GTPase HRas, N-terminally processed*ENSDARG0000000565185
nras / NRAS proto-oncogene, GTPase / P01111* / neuroblastoma ras oncogene*ENSDARG0000003822584
zgc:55558ENSDARG0000001316180
rras2 / RAS related 2 / P62070* / P62071* / Ras-related protein R-Ras2 *ENSDARG0000003625254
MRAS / si:ch73-116o1.2 / O08989* / O14807* / muscle and microspikes RAS* / muscle RAS oncogene homolog*ENSDARG0000007528553
mras / muscle RAS oncogene homolog / O08989* / O14807* / muscle and microspikes RAS*ENSDARG0000006286553
rras / RAS related / P10301* / P10833* / related RAS viral (r-ras) oncogene*ENSDARG0000000655353
ralaa / v-ral simian leukemia viral oncogene homolog Aa (ras related) / RALA* / P63321* / P11233* / RAS like proto-oncogene A* / Ras-related protein Ral-A *ENSDARG0000004546349
ralab / v-ral simian leukemia viral oncogene homolog Ab (ras related) / RALA* / P63321* / P11233* / RAS like proto-oncogene A* / Ras-related protein Ral-A *ENSDARG0000001625348
ralba / v-ral simian leukemia viral oncogene homolog Ba (ras related) / RALB* / Q9JIW9* / P11234* / RAS like proto-oncogene B* / Ras-related protein Ral-B *ENSDARG0000004077846
RERG / si:cabz01085950.1 / Q96A58* / RAS like estrogen regulated growth inhibitor*ENSDARG0000010463233
zgc:110699ENSDARG0000001747432
Q7SZ59 / rasl12 / RAS-like, family 12 / Q9NYN1*ENSDARG0000000270130
rrad / Ras-related associated with diabetes / P55042* / RRAD, Ras related glycolysis inhibitor and calcium channel regulator*ENSDARG0000005201130
si:dkeyp-59c12.1ENSDARG0000003811230
rergla / RERG/RAS-like a / RERGL* / Q9H628* / RERG like* / RERG/RAS-like*ENSDARG0000001939630
rem1 / RAS (RAD and GEM)-like GTP-binding 1 / O75628* / O35929* / GTP-binding protein REM 1 * / RRAD and GEM like GTPase 1*ENSDARG0000002054430
zgc:64022ENSDARG0000007070528
gem / GTP binding protein overexpressed in skeletal muscle / P55040* / P55041* / GTP-binding protein GEM *ENSDARG0000002911227


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IMP
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000010 cardiovascular system cardiovascular system nucleate erythrocyte absent , abnormal
Show

 ZFA:0000054 pericardium pericardium increased size , abnormal
Show

 ZFA:0000114 heart heart malformed , abnormal
Show

 ZFA:0000737 cranium cranium hypoplastic , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage hypoplastic , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch decreased size , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel disorganized , abnormal
intersegmental vessel aplastic , abnormal
intersegmental vessel brochidodromous , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage straight , abnormal
Show

 ZFA:0005035 subintestinal vein subintestinal vein disorganized , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte mislocalised , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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