ENSDARG00000006553


Danio rerio

Features
Gene ID: ENSDARG00000006553
  
Biological name :rras
  
Synonyms : RAS related / rras
  
Possible biological names infered from orthology : P10301 / P10833 / related RAS viral (r-ras) oncogene
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 32410746
Gene end: 32416121
  
Corresponding Affymetrix probe sets: Dr.6225.1.A1_at (Zebrafish Array)   NM_001005931_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000014099
Ensembl peptide - ENSDARP00000121131
Ensembl peptide - ENSDARP00000147347
NCBI entrez gene - 449660     See in Manteia.
RefSeq - NM_001005931
RefSeq Peptide - NP_001005931
swissprot - F1R5E5
swissprot - Q4V9D8
ZFIN ID - ZDB-GENE-041010-217
Ensembl - ENSDARG00000006553
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RRASENSG00000126458Homo sapiens
 RrasENSMUSG00000038387Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rras2 / RAS related 2 / P62070* / P62071* / Ras-related protein R-Ras2 *ENSDARG0000003625267
zgc:55558ENSDARG0000001316153
MRAS / si:ch73-116o1.2 / O08989* / O14807* / muscle and microspikes RAS* / muscle RAS oncogene homolog*ENSDARG0000007528553
mras / muscle RAS oncogene homolog / O08989* / O14807* / muscle and microspikes RAS*ENSDARG0000006286553
nras / NRAS proto-oncogene, GTPase / P01111* / neuroblastoma ras oncogene*ENSDARG0000003822552
hrasb / -Ha-ras Harvey rat sarcoma viral oncogene homolog b / HRAS* / P01112* / Q61411* / HRas proto-oncogene, GTPase* / GTPase HRas GTPase HRas, N-terminally processed*ENSDARG0000000565152
hrasa / v-Ha-ras Harvey rat sarcoma viral oncogene homolog a / HRAS* / P01112* / Q61411* / HRas proto-oncogene, GTPase* / GTPase HRas GTPase HRas, N-terminally processed*ENSDARG0000009849751
kras / v-Ki-ras2 Kirsten rat sarcoma viral oncogene homologENSDARG0000001084451
ralba / v-ral simian leukemia viral oncogene homolog Ba (ras related) / RALB* / Q9JIW9* / P11234* / RAS like proto-oncogene B* / Ras-related protein Ral-B *ENSDARG0000004077846
ralab / v-ral simian leukemia viral oncogene homolog Ab (ras related) / RALA* / P63321* / P11233* / RAS like proto-oncogene A* / Ras-related protein Ral-A *ENSDARG0000001625346
ralaa / v-ral simian leukemia viral oncogene homolog Aa (ras related) / RALA* / P63321* / P11233* / RAS like proto-oncogene A* / Ras-related protein Ral-A *ENSDARG0000004546345
zgc:110699ENSDARG0000001747430
rem1 / RAS (RAD and GEM)-like GTP-binding 1 / O75628* / O35929* / GTP-binding protein REM 1 * / RRAD and GEM like GTPase 1*ENSDARG0000002054429
rrad / Ras-related associated with diabetes / P55042* / RRAD, Ras related glycolysis inhibitor and calcium channel regulator*ENSDARG0000005201128
A1DZY4 / rasl11a / RAS-like, family 11, member A / Q6T310* / Q6IMB1* / Ras-like protein family member 11A *ENSDARG0000004601328
si:dkeyp-59c12.1ENSDARG0000003811228
gem / GTP binding protein overexpressed in skeletal muscle / P55040* / P55041* / GTP-binding protein GEM *ENSDARG0000002911227
RERG / si:cabz01085950.1 / Q96A58* / RAS like estrogen regulated growth inhibitor*ENSDARG0000010463227
Q7SZ59 / rasl12 / RAS-like, family 12 / Q9NYN1*ENSDARG0000000270127
zgc:64022ENSDARG0000007070526


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007219 Notch signaling pathway IMP
 biological_processGO:0045199 maintenance of epithelial cell apical/basal polarity IMP
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Sema4D mediated inhibition of cell attachment and migration
CREB phosphorylation through the activation of Ras


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001695 dorsolateral motor nucleus of vagal nerve dorsolateral motor nucleus of vagal nerve malformed , abnormal
Show

 ZFA:0007067 vagal ganglion vagal ganglion fused with vagal ganglion , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000017661 braf / B-Raf proto-oncogene, serine/threonine kinase / P15056* / P28028* / Serine/threonine-protein kinase B-raf *  / complex
 ENSDARG00000043010 Q6DEH3 / camk2d1 / calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1 / CAMK2D* / Q13557* / Q6PHZ2* / calcium/calmodulin dependent protein kinase II delta* / Mus musculus c...  / reaction






 

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