ENSDARG00000011600


Danio rerio

Features
Gene ID: ENSDARG00000011600
  
Biological name :epha4b
  
Synonyms : epha4b / eph receptor A4b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 40294313
Gene end: 40514151
  
Corresponding Affymetrix probe sets: Dr.12401.1.S1_at (Zebrafish Array)   NM_153658_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000030606
NCBI entrez gene - 64270     See in Manteia.
RefSeq - NM_153658
RefSeq Peptide - NP_705944
swissprot - F1RCL1
ZFIN ID - ZDB-GENE-030826-6
Ensembl - ENSDARG00000011600
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ek1 / eph-like kinase 1ENSDARG0000002008081
CT990561.1 / EPHA5* / P54756* / EPH receptor A5*ENSDARG0000005828463
epha7 / eph receptor A7 / Q15375* / Q61772* / Ephrin type-A receptor 7 *ENSDARG0000000463562
epha4l / eph receptor A4, like / EPHA4* / P54764* / Q03137* / EPH receptor A4* / Ephrin type-A receptor 4 *ENSDARG0000001076761
epha3 / eph receptor A3 / P29320*ENSDARG0000003937360
epha6 / eph receptor A6 / Q9UF33*ENSDARG0000002297158
ephb2b / eph receptor B2b / EPHB2* / P29323* / P54763* / EPH receptor B2* / Ephrin type-B receptor 2 *ENSDARG0000002153956
ephb2a / eph receptor B2a / EPHB2* / P29323* / P54763* / EPH receptor B2* / Ephrin type-B receptor 2 *ENSDARG0000003737356
ephb4b / eph receptor B4b / EPHB4* / P54760* / P54761* / EPH receptor B4* / Ephrin type-B receptor 4 *ENSDARG0000002711249
ephb3a / eph receptor B3a / EPHB3* / P54753* / P54754* / EPH receptor B3* / Ephrin type-B receptor 3 *ENSDARG0000003154849
ephb4a / eph receptor B4a / EPHB4* / P54760* / P54761* / EPH receptor B4* / Ephrin type-B receptor 4 *ENSDARG0000010072548
epha2b / eph receptor A2 bENSDARG0000002272747
epha2a / eph receptor A2 a / Epha2* / Q03145* / Ephrin type-A receptor 2 *ENSDARG0000001735446
ephb6 / eph receptor B6 / O08644* / Ephrin type-B receptor 6 *ENSDARG0000005772943
ephb1 / EPH receptor B1 / P54762* / Q8CBF3* / Ephrin type-B receptor 1 *ENSDARG0000007675740


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001090  Ephrin receptor ligand binding domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001426  Tyrosine-protein kinase, receptor class V, conserved site
 IPR001660  Sterile alpha motif domain
 IPR003961  Fibronectin type III
 IPR008266  Tyrosine-protein kinase, active site
 IPR008979  Galactose-binding-like domain superfamily
 IPR011009  Protein kinase-like domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016257  Ephrin receptor type-A /type-B
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR027936  Ephrin receptor, transmembrane domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030517 negative regulation of axon extension IGI
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 biological_processGO:0048685 negative regulation of collateral sprouting of intact axon in response to injury IGI
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005003 ephrin receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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