ENSDARG00000017354


Danio rerio

Features
Gene ID: ENSDARG00000017354
  
Biological name :epha2a
  
Synonyms : epha2a / eph receptor A2 a
  
Possible biological names infered from orthology : Epha2 / Ephrin type-A receptor 2 / Q03145
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 45874595
Gene end: 45905746
  
Corresponding Affymetrix probe sets: Dr.5765.1.S1_at (Zebrafish Array)   NM_131415_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000011069
NCBI entrez gene - 30689     See in Manteia.
RefSeq - NM_131415
RefSeq Peptide - NP_571490
swissprot - F1QSD6
ZFIN ID - ZDB-GENE-990415-63
Ensembl - ENSDARG00000017354
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Epha2ENSMUSG00000006445Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
epha2b / eph receptor A2 bENSDARG0000002272766
epha4b / eph receptor A4bENSDARG0000001160046
epha7 / eph receptor A7 / Q15375* / Q61772* / Ephrin type-A receptor 7 *ENSDARG0000000463546
epha6 / eph receptor A6 / Q9UF33*ENSDARG0000002297146
ephb2b / eph receptor B2b / EPHB2* / P29323* / P54763* / EPH receptor B2* / Ephrin type-B receptor 2 *ENSDARG0000002153946
ek1 / eph-like kinase 1ENSDARG0000002008046
epha4l / eph receptor A4, like / EPHA4* / P54764* / Q03137* / EPH receptor A4* / Ephrin type-A receptor 4 *ENSDARG0000001076745
CT990561.1 / EPHA5* / P54756* / EPH receptor A5*ENSDARG0000005828445
epha3 / eph receptor A3 / P29320*ENSDARG0000003937345
ephb2a / eph receptor B2a / EPHB2* / P29323* / P54763* / EPH receptor B2* / Ephrin type-B receptor 2 *ENSDARG0000003737345
ephb4a / eph receptor B4a / EPHB4* / P54760* / P54761* / EPH receptor B4* / Ephrin type-B receptor 4 *ENSDARG0000010072544
ephb4b / eph receptor B4b / EPHB4* / P54760* / P54761* / EPH receptor B4* / Ephrin type-B receptor 4 *ENSDARG0000002711243
ephb6 / eph receptor B6 / O08644* / Ephrin type-B receptor 6 *ENSDARG0000005772941
ephb3a / eph receptor B3a / EPHB3* / P54753* / P54754* / EPH receptor B3* / Ephrin type-B receptor 3 *ENSDARG0000003154841
ephb1 / EPH receptor B1 / P54762* / Q8CBF3* / Ephrin type-B receptor 1 *ENSDARG0000007675733


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001090  Ephrin receptor ligand binding domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001426  Tyrosine-protein kinase, receptor class V, conserved site
 IPR001660  Sterile alpha motif domain
 IPR003961  Fibronectin type III
 IPR008266  Tyrosine-protein kinase, active site
 IPR008979  Galactose-binding-like domain superfamily
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011009  Protein kinase-like domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016257  Ephrin receptor type-A /type-B
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR027936  Ephrin receptor, transmembrane domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005003 ephrin receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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