ENSDARG00000011876


Danio rerio

Features
Gene ID: ENSDARG00000011876
  
Biological name :ednraa
  
Synonyms : ednraa / endothelin receptor type Aa
  
Possible biological names infered from orthology : EDNRA / Endothelin-1 receptor / endothelin receptor type A / P25101 / Q61614
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 36612660
Gene end: 36702355
  
Corresponding Affymetrix probe sets: Dr.12576.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000146679
Ensembl peptide - ENSDARP00000151918
Ensembl peptide - ENSDARP00000149371
Ensembl peptide - ENSDARP00000146839
Ensembl peptide - ENSDARP00000002773
Ensembl peptide - ENSDARP00000108726
NCBI entrez gene - 114550     See in Manteia.
RefSeq - NM_001099445
RefSeq - XM_021476969
RefSeq Peptide - NP_001092915
swissprot - B3DLG5
swissprot - D0MQ51
swissprot - B8JIH1
ZFIN ID - ZDB-GENE-010906-2
Ensembl - ENSDARG00000011876
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EDNRAENSGALG00000010013Gallus gallus
 EDNRAENSG00000151617Homo sapiens
 EdnraENSMUSG00000031616Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ednrab / endothelin receptor type Ab / EDNRA* / P25101* / Q61614* / Endothelin-1 receptor * / endothelin receptor type A*ENSDARG0000006226265
ednrba / endothelin receptor Ba / EDNRB* / P24530* / endothelin receptor type B*ENSDARG0000008933454
ednrbb / endothelin receptor type Bb / EDNRB* / P24530* / P48302* / endothelin receptor type B*ENSDARG0000005349842
grpr / gastrin-releasing peptide receptor / P21729* / P30550*ENSDARG0000005662026
nmbr / neuromedin B receptor / O54799* / P28336*ENSDARG0000005415224
gpr37l1a / G protein-coupled receptor 37 like 1a / Q99JG2* / O60883* / GPR37L1* / G protein-coupled receptor 37 like 1*ENSDARG0000000607924
gpr37l1b / G protein-coupled receptor 37 like 1b / Q99JG2* / O60883* / GPR37L1* / G protein-coupled receptor 37 like 1*ENSDARG0000005677422
gpr37a / G protein-coupled receptor 37a / GPR37* / O15354* / Q9QY42* / Prosaposin receptor GPR37 * / G protein-coupled receptor 37*ENSDARG0000007456322
gpr37b / G protein-coupled receptor 37b / GPR37* / O15354* / Q9QY42* / Prosaposin receptor GPR37 * / G protein-coupled receptor 37*ENSDARG0000003329622


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000499  Endothelin receptor family
 IPR002175  Endothelin receptor A
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0010155 regulation of proton transport IMP
 biological_processGO:0042310 vasoconstriction IEA
 biological_processGO:0048484 enteric nervous system development IEA
 biological_processGO:0051216 cartilage development IMP
 biological_processGO:0086100 endothelin receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004962 endothelin receptor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0005327 vH ionocyte vH ionocyte regulation of pH process quality , abnormal
vH ionocyte ATP hydrolysis coupled proton transport rate , abnormal
vH ionocyte ATP hydrolysis coupled proton transport decreased rate , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000086669 edn3b / endothelin 3b / EDN3* / P14138* / P48299* / endothelin 3*  / complex / reaction
 ENSDARG00000070578 edn2 / endothelin 2 / P20800* / P22389*  / complex / reaction






 

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