ENSDARG00000086669


Danio rerio

Features
Gene ID: ENSDARG00000086669
  
Biological name :edn3b
  
Synonyms : edn3b / endothelin 3b
  
Possible biological names infered from orthology : EDN3 / endothelin 3 / P14138 / P48299
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 12072980
Gene end: 12106839
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000115695
NCBI entrez gene - 100148183     See in Manteia.
swissprot - E9QFS0
ZFIN ID - ZDB-GENE-090313-235
Ensembl - ENSDARG00000086669
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EDN3ENSGALG00000040880Gallus gallus
 EDN3ENSG00000124205Homo sapiens
 Edn3ENSMUSG00000027524Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
edn1 / endothelin 1 / P05305* / P22387* / Endothelin-1 Big endothelin-1*ENSDARG0000003691229
si:ch211-202p1.5ENSDARG0000009675527
edn2 / endothelin 2 / P20800* / P22389*ENSDARG0000007057825
CR855375.3 / EDN3* / P14138* / endothelin 3*ENSDARG0000010959122


Protein motifs (from Interpro)
Interpro ID Name
 IPR001928  Endothelin-like toxin
 IPR019764  Endothelin-like toxin, conserved site
 IPR020475  Endothelin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019229 regulation of vasoconstriction IEA
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0070285 pigment cell development IMP
 cellular_componentGO:0005576 extracellular region IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism decreased life span , ameliorated
whole organism neoplasm increased amount , abnormal
whole organism melanoma increased amount , ameliorated
Show

 ZFA:0005221 dorsal larval melanophore stripe dorsal larval melanophore stripe lacks parts or has fewer parts of type iridophore , abnormal
Show

 ZFA:0009091 melanocyte melanocyte shape , abnormal
melanocyte decreased amount , abnormal
melanocyte decreased pigmentation , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000011876 ednraa / endothelin receptor type Aa / EDNRA* / P25101* / Q61614* / Endothelin-1 receptor * / endothelin receptor type A*  / reaction / complex
 ENSDARG00000056618 xk / X-linked Kx blood group (McLeod syndrome) / P51811* / Q9QXY7* / X-linked Kx blood group*  / reaction
 ENSDARG00000089334 ednrba / endothelin receptor Ba / EDNRB* / P24530* / endothelin receptor type B*  / reaction / complex
 ENSDARG00000062262 ednrab / endothelin receptor type Ab / EDNRA* / P25101* / Q61614* / Endothelin-1 receptor * / endothelin receptor type A*  / complex / reaction
 ENSDARG00000076950 kel / Kell blood group, metallo-endopeptidase / P23276* / Q9EQF2* / Kell blood group glycoprotein homolog *  / reaction






 

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