ENSDARG00000036912


Danio rerio

Features
Gene ID: ENSDARG00000036912
  
Biological name :edn1
  
Synonyms : edn1 / endothelin 1
  
Possible biological names infered from orthology : Endothelin-1 Big endothelin-1 / P05305 / P22387
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 3376430
Gene end: 3381422
  
Corresponding Affymetrix probe sets: Dr.4076.1.S1_at (Zebrafish Array)   NM_131519_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000095917
NCBI entrez gene - 58032     See in Manteia.
RefSeq - NM_131519
RefSeq Peptide - NP_571594
swissprot - A5WW41
ZFIN ID - ZDB-GENE-000920-1
Ensembl - ENSDARG00000036912
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EDN1ENSGALG00000012735Gallus gallus
 EDN1ENSG00000078401Homo sapiens
 Edn1ENSMUSG00000021367Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
edn2 / endothelin 2 / P20800* / P22389*ENSDARG0000007057830
edn3b / endothelin 3b / EDN3* / P14138* / P48299* / endothelin 3*ENSDARG0000008666924
si:ch211-202p1.5ENSDARG0000009675521
CR855375.3 / EDN3* / P14138* / endothelin 3*ENSDARG0000010959115


Protein motifs (from Interpro)
Interpro ID Name
 IPR001928  Endothelin-like toxin
 IPR019764  Endothelin-like toxin, conserved site
 IPR020475  Endothelin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0014033 neural crest cell differentiation IMP
 biological_processGO:0019229 regulation of vasoconstriction IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0048899 anterior lateral line development IMP
 biological_processGO:0048901 anterior lateral line neuromast development IMP
 biological_processGO:0051216 cartilage development IMP
 biological_processGO:0060325 face morphogenesis IMP
 biological_processGO:0060349 bone morphogenesis IMP
 biological_processGO:0060351 cartilage development involved in endochondral bone morphogenesis IMP
 biological_processGO:0060536 cartilage morphogenesis IMP
 biological_processGO:1904888 cranial skeletal system development IMP
 cellular_componentGO:0005576 extracellular region IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain absent , abnormal
Show

 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton quality , abnormal
Show

 ZFA:0000136 otic lateral line neuromast otic lateral line neuromast decreased amount , abnormal
Show

 ZFA:0000184 cleithrum cleithrum decreased length , abnormal
cleithrum malformed , abnormal
Show

 ZFA:0000191 dentary dentary fused with maxilla , abnormal
dentary malformed , abnormal
dentary curved caudal , abnormal
Show

 ZFA:0000236 mandibular muscle mandibular muscle wholly dorsalized , abnormal
Show

 ZFA:0000250 opercle opercle size , abnormal
opercle increased size , abnormal
opercle decreased size , abnormal
opercle shape , abnormal
opercle increased width , abnormal
opercle cartilaginous joint increased thickness , abnormal
opercle cartilaginous joint distended , abnormal
opercle increased variability of size , abnormal
opercle aplastic , abnormal
Show

 ZFA:0000270 maxilla maxilla malformed , abnormal
maxilla curved caudal , abnormal
Show

 ZFA:0000422 retroarticular retroarticular absent , abnormal
Show

 ZFA:0000476 branchiostegal ray branchiostegal ray position , abnormal
branchiostegal ray malformed , abnormal
branchiostegal ray falciform , abnormal
branchiostegal ray decreased size , abnormal
Show

 ZFA:0000547 mouth mouth quality , abnormal
mouth concave 3-D shape , abnormal
Show

 ZFA:0000692 symplectic symplectic decreased size , abnormal
symplectic absent , abnormal
Show

 ZFA:0000813 infraorbital lateral line neuromast infraorbital lateral line neuromast decreased amount , abnormal
Show

 ZFA:0000814 opercular lateral line neuromast opercular lateral line neuromast absent , abnormal
opercular lateral line neuromast decreased amount , abnormal
opercular lateral line neuromast mislocalised dorsally , abnormal
Show

 ZFA:0000939 middle lateral line neuromast middle lateral line neuromast decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
Show

 ZFA:0001114 head head lacks all parts of type ventral intermandibularis anterior , abnormal
head lacks all parts of type ventral intermandibularis posterior , abnormal
Show

 ZFA:0001128 pharyngeal pouch 1 pharyngeal pouch 1 physical object quality , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage aplastic , abnormal
Meckels cartilage decreased size , abnormal
Meckels cartilage morphology , abnormal
Meckels cartilage absent , abnormal
Meckels cartilage bent , abnormal
Meckels cartilage fused with palatoquadrate cartilage , abnormal
Meckels cartilage protruding , abnormal
Meckels cartilage mislocalised posteriorly , abnormal
Show

 ZFA:0001216 splanchnocranium splanchnocranium quality , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton joint absent , abnormal
Show

 ZFA:0001228 pharyngeal arch 3 skeleton pharyngeal arch 3 skeleton decreased length , abnormal
Show

 ZFA:0001231 pharyngeal arch 4 skeleton pharyngeal arch 4 skeleton decreased length , abnormal
Show

 ZFA:0001239 ceratobranchial 5 bone ceratobranchial 5 bone decreased length , abnormal
ceratobranchial 5 bone malformed , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch orientation eye , abnormal
ventral mandibular arch aplastic , abnormal
ventral mandibular arch decreased size , abnormal
Show

 ZFA:0001276 pharyngeal arch 2 skeleton pharyngeal arch 2 skeleton decreased size , abnormal
Show

 ZFA:0001290 stomodeum stomodeum mislocalised ventrally , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch absent , abnormal
pharyngeal arch decreased amount , abnormal
pharyngeal arch ventral region increased amount , abnormal
pharyngeal arch ventral region decreased amount , abnormal
pharyngeal arch neural crest cell increased amount , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage fused with Meckels cartilage , abnormal
palatoquadrate cartilage decreased size , abnormal
palatoquadrate cartilage increased length , abnormal
palatoquadrate cartilage fused with hyosymplectic cartilage , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage aplastic , abnormal
ceratohyal cartilage deformed , abnormal
ceratohyal cartilage decreased size , abnormal
ceratohyal cartilage absent , abnormal
ceratohyal cartilage morphology , abnormal
ceratohyal cartilage structure , abnormal
ceratohyal cartilage inverted , abnormal
Show

 ZFA:0001402 ventral hyoid arch ventral hyoid arch morphology , abnormal
ventral hyoid arch mislocalised , abnormal
Show

 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage aplastic , abnormal
hyosymplectic cartilage fused with ceratohyal cartilage , abnormal
hyosymplectic cartilage increased width , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage ventral region morphology , abnormal
pharyngeal arch cartilage ventral region decreased amount , abnormal
Show

 ZFA:0001472 anterior lateral line neuromast anterior lateral line neuromast increased amount , abnormal
anterior lateral line neuromast mislocalised , abnormal
Show

 ZFA:0001510 basihyal cartilage basihyal cartilage deformed , abnormal
Show

 ZFA:0001511 interhyal cartilage interhyal cartilage absent , abnormal
Show

 ZFA:0001606 pharyngeal arch 3 pharyngeal arch 3 ventral region physical object quality , abnormal
pharyngeal arch 3 mesenchymal cell physical object quality , abnormal
Show

 ZFA:0001607 pharyngeal arch 4 pharyngeal arch 4 ventral region physical object quality , abnormal
pharyngeal arch 4 mesenchymal cell physical object quality , abnormal
Show

 ZFA:0001611 pharyngeal arch 2 pharyngeal arch 2 malformed , abnormal
pharyngeal arch 2 ventral region physical object quality , abnormal
pharyngeal arch 2 mesenchymal cell physical object quality , abnormal
pharyngeal arch 2 joint absent , abnormal
pharyngeal arch 2 decreased amount , abnormal
pharyngeal arch 2 ventral region increased amount , abnormal
pharyngeal arch 2 ventral region decreased amount , abnormal
pharyngeal arch 2 ventral region decreased size , abnormal
pharyngeal arch 2 position , abnormal
pharyngeal arch 2 medial region decreased amount , abnormal
pharyngeal arch 2 ventral region absent , abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 mesenchyme physical object quality , abnormal
pharyngeal arch 1 decreased length , abnormal
pharyngeal arch 1 mesenchyme decreased area , abnormal
pharyngeal arch 1 malformed , abnormal
pharyngeal arch 1 ventral region physical object quality , abnormal
pharyngeal arch 1 mesenchymal cell physical object quality , abnormal
pharyngeal arch 1 joint physical object quality , abnormal
pharyngeal arch 1 ventral region decreased size , abnormal
pharyngeal arch 1 ventral region decreased amount , abnormal
pharyngeal arch 1 position , abnormal
pharyngeal arch 1 medial region decreased amount , abnormal
pharyngeal arch 1 ventral region absent , abnormal
Show

 ZFA:0005465 ceratohyal-branchiostegal ray joint ceratohyal-branchiostegal ray joint morphology , abnormal
Show

 ZFA:0005473 interhyal-epihyal joint interhyal-epihyal joint absent , abnormal
Show

 ZFA:0007008 ventral intermandibularis anterior ventral intermandibularis anterior physical object quality , abnormal
Show

 ZFA:0007048 ventral intermandibularis posterior ventral intermandibularis posterior physical object quality , abnormal
Show

 ZFA:0007051 interhyoideus interhyoideus decreased length , abnormal
interhyoideus physical object quality , abnormal
Show

 ZFA:0007052 hyohyoideus hyohyoideus decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr