ENSDARG00000012215


Danio rerio

Features
Gene ID: ENSDARG00000012215
  
Biological name :umps
  
Synonyms : umps / uridine monophosphate synthetase
  
Possible biological names infered from orthology : P11172 / P13439
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 11576502
Gene end: 11587070
  
Corresponding Affymetrix probe sets: Dr.8999.1.S1_at (Zebrafish Array)   NM_200174_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000035728
NCBI entrez gene - 393143     See in Manteia.
RefSeq - NM_200174
RefSeq Peptide - NP_956468
swissprot - B8JLL1
ZFIN ID - ZDB-GENE-040426-785
Ensembl - ENSDARG00000012215
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UMPSENSGALG00000011770Gallus gallus
 UMPSENSG00000114491Homo sapiens
 UmpsENSMUSG00000022814Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000836  Phosphoribosyltransferase domain
 IPR001754  Orotidine 5"-phosphate decarboxylase domain
 IPR011060  Ribulose-phosphate binding barrel
 IPR013785  Aldolase-type TIM barrel
 IPR018089  Orotidine 5"-phosphate decarboxylase, active site
 IPR023031  Orotate phosphoribosyltransferase
 IPR029057  Phosphoribosyltransferase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006207 "de novo" pyrimidine nucleobase biosynthetic process IEA
 biological_processGO:0006221 pyrimidine nucleotide biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009116 nucleoside metabolic process IEA
 biological_processGO:0044205 "de novo" UMP biosynthetic process IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004588 orotate phosphoribosyltransferase activity IEA
 molecular_functionGO:0004590 orotidine-5"-phosphate decarboxylase activity IEA


Pathways (from Reactome)
Pathway description
Pyrimidine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000012215 umps / uridine monophosphate synthetase / P11172*  / complex






 

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contact: otassy@igbmc.fr