ENSMUSG00000022814


Mus musculus

Features
Gene ID: ENSMUSG00000022814
  
Biological name :Umps
  
Synonyms : P13439 / Umps / uridine monophosphate synthetase
  
Possible biological names infered from orthology : P11172
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B3
Gene start: 33954782
Gene end: 33967038
  
Corresponding Affymetrix probe sets: 10439130 (MoGene1.0st)   1434859_at (Mouse Genome 430 2.0 Array)   1451445_at (Mouse Genome 430 2.0 Array)   1455832_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023510
Ensembl peptide - ENSMUSP00000119423
NCBI entrez gene - 22247     See in Manteia.
MGI - MGI:1298388
RefSeq - XM_006522008
RefSeq - NM_001348087
RefSeq - NM_009471
RefSeq Peptide - NP_001335016
RefSeq Peptide - NP_033497
swissprot - P13439
swissprot - Q544K9
swissprot - D6RJ62
Ensembl - ENSMUSG00000022814
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 umpsENSDARG00000012215Danio rerio
 UMPSENSGALG00000011770Gallus gallus
 UMPSENSG00000114491Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000836  Phosphoribosyltransferase domain
 IPR001754  Orotidine 5"-phosphate decarboxylase domain
 IPR004467  Orotate phosphoribosyl transferase domain
 IPR011060  Ribulose-phosphate binding barrel
 IPR013785  Aldolase-type TIM barrel
 IPR014732  Orotidine 5"-phosphate decarboxylase
 IPR018089  Orotidine 5"-phosphate decarboxylase, active site
 IPR023031  Orotate phosphoribosyltransferase
 IPR029057  Phosphoribosyltransferase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006207 "de novo" pyrimidine nucleobase biosynthetic process IEA
 biological_processGO:0006221 pyrimidine nucleotide biosynthetic process IEA
 biological_processGO:0006222 UMP biosynthetic process IEA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0007595 lactation IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009116 nucleoside metabolic process IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0044205 "de novo" UMP biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004588 orotate phosphoribosyltransferase activity ISO
 molecular_functionGO:0004590 orotidine-5"-phosphate decarboxylase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
Pyrimidine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022814 Umps / P13439 / uridine monophosphate synthetase / P11172*  / complex






 

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