ENSDARG00000012555


Danio rerio

Features
Gene ID: ENSDARG00000012555
  
Biological name :ak5
  
Synonyms : adenylate kinase 5 / ak5
  
Possible biological names infered from orthology : Adenylate kinase isoenzyme 5 / Q920P5 / Q9Y6K8
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 8845840
Gene end: 9059955
  
Corresponding Affymetrix probe sets: Dr.9425.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000027924
NCBI entrez gene - 100003595     See in Manteia.
swissprot - A5PMF1
ZFIN ID - ZDB-GENE-030131-8256
Ensembl - ENSDARG00000012555
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AK5ENSGALG00000031652Gallus gallus
 AK5ENSG00000154027Homo sapiens
 Ak5ENSMUSG00000039058Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ak5l / adenylate kinase 5, likeENSDARG0000001773925
ak1 / adenylate kinase 1 / P00568*ENSDARG0000000195012
cmpk / cytidylate kinase / CMPK1* / P30085* / cytidine/uridine monophosphate kinase 1*ENSDARG0000001992410


Protein motifs (from Interpro)
Interpro ID Name
 IPR000850  Adenylate kinase/UMP-CMP kinase
 IPR003117  cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR033690  Adenylate kinase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0060271 cilium assembly IMP
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019205 nucleobase-containing compound kinase activity IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain hydrocephalic , abnormal
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 ZFA:0000047 peripheral olfactory organ peripheral olfactory organ cilium morphology , abnormal
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 ZFA:0000114 heart heart edematous , abnormal
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 ZFA:0001117 post-vent region post-vent region curved , abnormal
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 ZFA:0001617 otolith otolith malformed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000012555 ak5 / adenylate kinase 5 / Q920P5* / Q9Y6K8* / Adenylate kinase isoenzyme 5 *  / complex






 

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contact: otassy@igbmc.fr