ENSG00000154027


Homo sapiens

Features
Gene ID: ENSG00000154027
  
Biological name :AK5
  
Synonyms : adenylate kinase 5 / AK5 / Q9Y6K8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p31.1
Gene start: 77282051
Gene end: 77559969
  
Corresponding Affymetrix probe sets: 219308_s_at (Human Genome U133 Plus 2.0 Array)   222862_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436859
Ensembl peptide - ENSP00000346577
Ensembl peptide - ENSP00000433915
Ensembl peptide - ENSP00000434409
Ensembl peptide - ENSP00000341430
NCBI entrez gene - 26289     See in Manteia.
OMIM - 608009
RefSeq - XM_017001012
RefSeq - XM_005270739
RefSeq - XM_006710572
RefSeq - XM_017001008
RefSeq - XM_017001009
RefSeq - XM_017001010
RefSeq - XM_017001011
RefSeq - NM_012093
RefSeq - NM_174858
RefSeq Peptide - NP_036225
RefSeq Peptide - NP_777283
swissprot - E9PQQ8
swissprot - H0YEZ1
swissprot - Q9Y6K8
swissprot - E9PIS7
Ensembl - ENSG00000154027
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ak5ENSDARG00000012555Danio rerio
 AK5ENSGALG00000031652Gallus gallus
 Ak5ENSMUSG00000039058Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AK1 / P00568 / adenylate kinase 1ENSG0000010699221
CMPK1 / P30085 / cytidine/uridine monophosphate kinase 1ENSG0000016236814


Protein motifs (from Interpro)
Interpro ID Name
 IPR000850  Adenylate kinase/UMP-CMP kinase
 IPR006267  Adenylate kinase, isozyme 1/5
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR033690  Adenylate kinase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006165 nucleoside diphosphate phosphorylation IDA
 biological_processGO:0006172 ADP biosynthetic process TAS
 biological_processGO:0006173 dADP biosynthetic process TAS
 biological_processGO:0009142 nucleoside triphosphate biosynthetic process IDA
 biological_processGO:0009220 pyrimidine ribonucleotide biosynthetic process TAS
 biological_processGO:0015949 nucleobase-containing small molecule interconversion TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046034 ATP metabolic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004017 adenylate kinase activity TAS
 molecular_functionGO:0004550 nucleoside diphosphate kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019205 nucleobase-containing compound kinase activity IEA
 molecular_functionGO:0019206 nucleoside kinase activity EXP


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000154027 AK5 / Q9Y6K8 / adenylate kinase 5  / complex






 

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