ENSDARG00000013251


Danio rerio

Features
Gene ID: ENSDARG00000013251
  
Biological name :hsf4
  
Synonyms : heat shock transcription factor 4 / hsf4
  
Possible biological names infered from orthology : Heat shock factor protein 4 / Q9R0L1 / Q9ULV5
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 22739732
Gene end: 22753637
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000025988
Ensembl peptide - ENSDARP00000150156
NCBI entrez gene - 503739     See in Manteia.
RefSeq - NM_001328208
RefSeq Peptide - NP_001315137
swissprot - Q5CZP2
ZFIN ID - ZDB-GENE-050306-18
Ensembl - ENSDARG00000013251
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HSF4ENSGALG00000003224Gallus gallus
 HSF4ENSG00000102878Homo sapiens
 Hsf4ENSMUSG00000033249Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hsf1 / heat shock transcription factor 1 / P38532* / Q00613* / heat shock factor 1*ENSDARG0000000881852
hsf2 / heat shock transcription factor 2 / Q03933*ENSDARG0000005309742
si:dkey-18a10.3ENSDARG0000009081436


Protein motifs (from Interpro)
Interpro ID Name
 IPR000232  Heat shock factor (HSF)-type, DNA-binding
 IPR010542  Vertebrate heat shock transcription factor, C-terminal domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR027725  Heat shock transcription factor family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002089 lens morphogenesis in camera-type eye IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0032077 positive regulation of deoxyribonuclease activity IMP
 biological_processGO:0070306 lens fiber cell differentiation IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000035 lens lens nucleate quality , abnormal
lens chromatin damaged , abnormal
lens opaque , abnormal
lens decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism absent , abnormal
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 ZFA:0001326 lens epithelium lens epithelium epithelial cell increased amount , abnormal
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 ZFA:0009401 lens fiber cell lens fiber cell nucleus present , abnormal
lens fiber cell increased amount , abnormal
lens fiber cell disorganized , abnormal
lens fiber cell early endosome present , abnormal
lens fiber cell late endosome present , abnormal
lens fiber cell late endosome mislocalised , abnormal
lens fiber cell organelle present , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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