ENSDARG00000015449


Danio rerio

Features
Gene ID: ENSDARG00000015449
  
Biological name :fut8a
  
Synonyms : fucosyltransferase 8a (alpha (1,6) fucosyltransferase) / fut8a
  
Possible biological names infered from orthology : Alpha-(1,6)-fucosyltransferase / fucosyltransferase 8 / FUT8 / Q9BYC5 / Q9WTS2
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 33719415
Gene end: 33906488
  
Corresponding Affymetrix probe sets: Dr.5303.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000122544
Ensembl peptide - ENSDARP00000156546
NCBI entrez gene - 797512     See in Manteia.
RefSeq - XM_005158746
swissprot - F1QW63
ZFIN ID - ZDB-GENE-031118-20
Ensembl - ENSDARG00000015449
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FUT8ENSGALG00000036443Gallus gallus
 FUT8ENSG00000033170Homo sapiens
 Fut8ENSMUSG00000021065Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fut8b / fucosyltransferase 8b (alpha (1,6) fucosyltransferase) / FUT8* / Q9BYC5* / fucosyltransferase 8*ENSDARG0000008811782


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR015827  Alpha-(1,6)-fucosyltransferase
 IPR027350  Glycosyltransferase family 23 (GT23) domain
 IPR035653  Alpha-(1,6)-fucosyltransferase, SH3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006487 protein N-linked glycosylation IBA
 biological_processGO:0033578 protein glycosylation in Golgi IEA
 biological_processGO:0036071 N-glycan fucosylation IMP
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 molecular_functionGO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0046921 alpha-(1->6)-fucosyltransferase activity IMP


Pathways (from Reactome)
Pathway description
Reactions specific to the complex N-glycan synthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord lacks all parts of type motor neuron neuron projection, abnormal
Show

 ZFA:0000107 eye eye decreased distance eye , abnormal
eye decreased size , abnormal
eye physical object quality , abnormal
Show

 ZFA:0000109 forebrain forebrain decreased size , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle swollen , abnormal
Show

 ZFA:0000137 optic stalk optic stalk decreased length , abnormal
optic stalk increased thickness , abnormal
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 ZFA:0000152 retina retina lacks parts or has fewer parts of type Muller cell , abnormal
retina structure , abnormal
retina decreased size , abnormal
retina lacks parts or has fewer parts of type retinal ganglion cell , abnormal
Show

 ZFA:0000155 somite somite U-shaped , abnormal
somite has fewer parts of type slow muscle cell , abnormal
somite muscle cell decreased length , abnormal
Show

 ZFA:0000453 cranial nerve X cranial nerve X position , abnormal
Show

 ZFA:0001094 whole organism whole organism increased curvature , abnormal
whole organism lacks all parts of type optic chiasm , abnormal
whole organism lacks all parts of type dorsal root ganglion neuron projection, abnormal
Show

 ZFA:0001216 splanchnocranium splanchnocranium lacks all parts of type mandibular arch skeleton , abnormal
Show

 ZFA:0001692 hindbrain commissure hindbrain commissure decreased amount , abnormal
Show

 ZFA:0009052 motor neuron motor neuron position , abnormal
motor neuron disorganized , abnormal
Show

 ZFA:0009127 photoreceptor cell photoreceptor cell decreased amount , abnormal
Show

 ZFA:0009165 neural crest cell neural crest cell position , abnormal
Show

 ZFA:0009310 retinal ganglion cell retinal ganglion cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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