ENSDARG00000015628


Danio rerio

Features
Gene ID: ENSDARG00000015628
  
Biological name :psmd10
  
Synonyms : proteasome 26S subunit, non-ATPase 10 / psmd10
  
Possible biological names infered from orthology : O75832 / proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 / Q9Z2X2
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 28464736
Gene end: 28469244
  
Corresponding Affymetrix probe sets: Dr.10290.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000010745
NCBI entrez gene - 403085     See in Manteia.
swissprot - Q6TGV5
ZFIN ID - ZDB-GENE-050112-1
Ensembl - ENSDARG00000015628
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PSMD10ENSGALG00000008287Gallus gallus
 O75832ENSG00000101843Homo sapiens
 Psmd10ENSMUSG00000031429Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ankrd1a / ankyrin repeat domain 1a (cardiac muscle) / ANKRD1* / Q15327* / Q9CR42* / ankyrin repeat domain 1* / Ankyrin repeat domain-containing protein 1 *ENSDARG0000007526328
ankrd1b / ankyrin repeat domain 1b (cardiac muscle) / ANKRD1* / Q15327* / Q9CR42* / ankyrin repeat domain 1* / Ankyrin repeat domain-containing protein 1 *ENSDARG0000007619228
ankef1a / ankyrin repeat and EF-hand domain containing 1a / ANKEF1* / Q9D2J7* / Q9NU02* / ankyrin repeat and EF-hand domain containing 1* / Ankyrin repeat and EF-hand domain-containing protein 1 *ENSDARG0000001913526
asb8 / ankyrin repeat and SOCS box containing 8 / Q9H765*ENSDARG0000000338325
ankef1b / ankyrin repeat and EF-hand domain containing 1b / ANKEF1* / Q9D2J7* / Q9NU02* / ankyrin repeat and EF-hand domain containing 1* / Ankyrin repeat and EF-hand domain-containing protein 1 *ENSDARG0000006021125
ankrd2 / ankyrin repeat domain 2 (stretch responsive muscle) / Q9WV06* / Q9GZV1* / ankyrin repeat domain 2* / Ankyrin repeat domain-containing protein 2 *ENSDARG0000000272223
Q6DGX3 / ankrd54 / ankyrin repeat domain 54 / Q6NXT1* / Q91WK7* / Ankyrin repeat domain-containing protein 54 *ENSDARG0000005574320


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055088 lipid homeostasis IMP
 cellular_componentGO:0000502 proteasome complex IEA


Pathways (from Reactome)
Pathway description
Activation of NF-kappaB in B cells
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Cross-presentation of soluble exogenous antigens (endosomes)
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
SCF(Skp2)-mediated degradation of p27/p21
Degradation of beta-catenin by the destruction complex
Downstream TCR signaling
Separation of Sister Chromatids
FCERI mediated NF-kB activation
Autodegradation of the E3 ubiquitin ligase COP1
Regulation of ornithine decarboxylase (ODC)
ABC-family proteins mediated transport
AUF1 (hnRNP D0) binds and destabilizes mRNA
Asymmetric localization of PCP proteins
Degradation of AXIN
Degradation of DVL
Dectin-1 mediated noncanonical NF-kB signaling
CLEC7A (Dectin-1) signaling
Degradation of GLI1 by the proteasome
Hedgehog on state
Regulation of RAS by GAPs
TNFR2 non-canonical NF-kB pathway
NIK-->noncanonical NF-kB signaling
MAPK6/MAPK4 signaling
UCH proteinases
Ub-specific processing proteases
CDT1 association with the CDC6:ORC:origin complex
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
Ubiquitin-dependent degradation of Cyclin D1
G2/M Checkpoints
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
The role of GTSE1 in G2/M progression after G2 checkpoint
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Regulation of RUNX2 expression and activity
Regulation of RUNX3 expression and activity
Regulation of PTEN stability and activity
Neddylation
Interleukin-1 signaling
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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