ENSDARG00000016010


Danio rerio

Features
Gene ID: ENSDARG00000016010
  
Biological name :nup107
  
Synonyms : nucleoporin 107 / nup107
  
Possible biological names infered from orthology : Nuclear pore complex protein Nup107 / P57740 / Q8BH74
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 22730795
Gene end: 22749553
  
Corresponding Affymetrix probe sets: Dr.9746.9.A1_at (Zebrafish Array)   NM_001030167_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000040032
NCBI entrez gene - 562350     See in Manteia.
RefSeq - NM_001030167
RefSeq Peptide - NP_001025338
swissprot - Q5RGI2
ZFIN ID - ZDB-GENE-041210-245
Ensembl - ENSDARG00000016010
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NUP107ENSGALG00000009934Gallus gallus
 NUP107ENSG00000111581Homo sapiens
 Nup107ENSMUSG00000052798Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007252  Nuclear pore protein 84/107


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery IBA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006406 mRNA export from nucleus IMP
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0051292 nuclear pore complex assembly IMP
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0031080 nuclear pore outer ring IBA
 molecular_functionGO:0017056 structural constituent of nuclear pore IBA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of Mature mRNA derived from an Intron-Containing Transcript
Regulation of Glucokinase by Glucokinase Regulatory Protein
snRNP Assembly
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
Transcriptional regulation by small RNAs
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
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 ZFA:0000056 pharynx pharynx decreased width , abnormal
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 ZFA:0000076 swim bladder swim bladder uninflated , abnormal
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 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton chondroblast absent , abnormal
pharyngeal arch 3-7 skeleton chondrocyte absent , abnormal
pharyngeal arch 3-7 skeleton absent , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000152 retina retina nuclear pore aggregated , abnormal
retina nuclear pore malformed , abnormal
retina apoptotic process increased process quality , abnormal
retina poly(A)+ mRNA export from nucleus decreased process quality , abnormal
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 ZFA:0000445 optic tectum optic tectum nuclear pore aggregated , abnormal
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 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism decreased length , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage absent , abnormal
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 ZFA:0001288 renal glomerulus renal glomerulus morphology , abnormal
renal glomerulus basement membrane morphology , abnormal
renal glomerulus basement membrane increased thickness , abnormal
renal glomerulus podocyte foot shape , abnormal
renal glomerulus hypoplastic , abnormal
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 ZFA:0001306 pharyngeal arch pharyngeal arch chondroblast has fewer parts of type chondroblast nuclear pore, abnormal
pharyngeal arch nuclear pore aggregated , abnormal
pharyngeal arch malformed , abnormal
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 ZFA:0001338 intestine intestine decreased size , abnormal
intestine smooth , abnormal
intestine nuclear pore aggregated , abnormal
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 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage absent , abnormal
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 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer absent , abnormal
retinal outer nuclear layer disorganized , abnormal
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 ZFA:0001611 pharyngeal arch 2 pharyngeal arch 2 chondroblast decreased amount , abnormal
pharyngeal arch 2 chondrocyte decreased amount , abnormal
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 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 chondroblast decreased amount , abnormal
pharyngeal arch 1 chondrocyte decreased amount , abnormal
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 ZFA:0005124 intestinal epithelium intestinal epithelium nuclear pore decreased amount , abnormal
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 ZFA:0005284 glomerular capillary glomerular capillary collapsed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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