ENSDARG00000016415


Danio rerio

Features
Gene ID: ENSDARG00000016415
  
Biological name :dhtkd1
  
Synonyms : dehydrogenase E1 and transketolase domain containing 1 / dhtkd1
  
Possible biological names infered from orthology : A2ATU0 / Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial / Q96HY7
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 8031999
Gene end: 8055229
  
Corresponding Affymetrix probe sets: Dr.13396.1.S1_at (Zebrafish Array)   NM_001008619_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000025776
NCBI entrez gene - 494076     See in Manteia.
RefSeq - NM_001008619
RefSeq Peptide - NP_001008619
swissprot - F1R838
ZFIN ID - ZDB-GENE-041212-44
Ensembl - ENSDARG00000016415
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DHTKD1ENSGALG00000003674Gallus gallus
 DHTKD1ENSG00000181192Homo sapiens
 A2ATU0ENSMUSG00000025815Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ogdhb / oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide) / OGDH* / Q60597* / Q02218* / oxoglutarate dehydrogenase* / 2-oxoglutarate dehydrogenase, mitochondrial *ENSDARG0000010342837
ogdhl / oxoglutarate dehydrogenase like / Q9ULD0*ENSDARG0000007924937
ogdha / oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide) / OGDH* / Q60597* / Q02218* / oxoglutarate dehydrogenase* / 2-oxoglutarate dehydrogenase, mitochondrial *ENSDARG000000342702


Protein motifs (from Interpro)
Interpro ID Name
 IPR001017  Dehydrogenase, E1 component
 IPR005475  Transketolase-like, pyrimidine-binding domain
 IPR011603  2-oxoglutarate dehydrogenase E1 component
 IPR029061  Thiamin diphosphate-binding fold
 IPR031717  Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity IEA
 molecular_functionGO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEA
 molecular_functionGO:0030976 thiamine pyrophosphate binding IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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