ENSGALG00000003674


Gallus gallus

Features
Gene ID: ENSGALG00000003674
  
Biological name :DHTKD1
  
Synonyms : dehydrogenase E1 and transketolase domain containing 1 / DHTKD1
  
Possible biological names infered from orthology : A2ATU0 / Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial / Q96HY7
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 6275964
Gene end: 6292436
  
Corresponding Affymetrix probe sets: GgaAffx.1010.1.S1_at (Chicken Array)   GgaAffx.220.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005812
Ensembl peptide - ENSGALP00000049166
NCBI entrez gene - 426076     See in Manteia.
RefSeq - XM_423753
swissprot - A0A1D5P8W7
swissprot - F1NQC6
Ensembl - ENSGALG00000003674
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhtkd1ENSDARG00000016415Danio rerio
 DHTKD1ENSG00000181192Homo sapiens
 A2ATU0ENSMUSG00000025815Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OGDH / oxoglutarate dehydrogenase / Q02218* / Q60597* / 2-oxoglutarate dehydrogenase, mitochondrial *ENSGALG0000001415538
OGDHL / oxoglutarate dehydrogenase like / Q9ULD0*ENSGALG0000000226637


Protein motifs (from Interpro)
Interpro ID Name
 IPR001017  Dehydrogenase, E1 component
 IPR005475  Transketolase-like, pyrimidine-binding domain
 IPR011603  2-oxoglutarate dehydrogenase E1 component
 IPR029061  Thiamin diphosphate-binding fold
 IPR031717  Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0006091 generation of precursor metabolites and energy IEA
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0045252 oxoglutarate dehydrogenase complex IBA
 molecular_functionGO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity IEA
 molecular_functionGO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEA
 molecular_functionGO:0030976 thiamine pyrophosphate binding IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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