ENSMUSG00000025815


Mus musculus

Features
Gene ID: ENSMUSG00000025815
  
Biological name :Dhtkd1
  
Synonyms : A2ATU0 / Dhtkd1 / Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
  
Possible biological names infered from orthology : dehydrogenase E1 and transketolase domain containing 1 / Q96HY7
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A1
Gene start: 5896115
Gene end: 5942792
  
Corresponding Affymetrix probe sets: 10479902 (MoGene1.0st)   1457027_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026924
Ensembl peptide - ENSMUSP00000092769
NCBI entrez gene - 209692     See in Manteia.
MGI - MGI:2445096
RefSeq - XM_017316879
RefSeq - NM_001081131
RefSeq - XM_017316877
RefSeq - XM_017316878
RefSeq - XM_006497447
RefSeq Peptide - NP_001074600
swissprot - A2ATU0
Ensembl - ENSMUSG00000025815
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhtkd1ENSDARG00000016415Danio rerio
 DHTKD1ENSGALG00000003674Gallus gallus
 DHTKD1ENSG00000181192Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ogdhl / oxoglutarate dehydrogenase-like / Q9ULD0*ENSMUSG0000002191339
Ogdh / Q60597 / 2-oxoglutarate dehydrogenase, mitochondrial / Q02218* / oxoglutarate dehydrogenase*ENSMUSG0000002045637


Protein motifs (from Interpro)
Interpro ID Name
 IPR001017  Dehydrogenase, E1 component
 IPR005475  Transketolase-like, pyrimidine-binding domain
 IPR011603  2-oxoglutarate dehydrogenase E1 component
 IPR029061  Thiamin diphosphate-binding fold
 IPR031717  Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IGI
 biological_processGO:0006091 generation of precursor metabolites and energy ISS
 biological_processGO:0006096 glycolytic process IEA
 biological_processGO:0006099 tricarboxylic acid cycle IBA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0045252 oxoglutarate dehydrogenase complex IBA
 molecular_functionGO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEA
 molecular_functionGO:0030976 thiamine pyrophosphate binding IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000034424 Gcsh / Q91WK5 / Glycine cleavage system H protein, mitochondrial / P23434* / AC092718.3* / AC092718.8* / glycine cleavage system protein H*  / reaction






 

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