ENSGALG00000014155


Gallus gallus

Features
Gene ID: ENSGALG00000014155
  
Biological name :OGDH
  
Synonyms : OGDH / oxoglutarate dehydrogenase
  
Possible biological names infered from orthology : 2-oxoglutarate dehydrogenase, mitochondrial / Q02218 / Q60597
  
Species: Gallus gallus
  
Chr. number: 22
Strand: 1
Band:
Gene start: 4622986
Gene end: 4643736
  
Corresponding Affymetrix probe sets: Gga.7238.1.S1_s_at (Chicken Array)   Gga.7238.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049276
Ensembl peptide - ENSGALP00000028857
NCBI entrez gene - 426429     See in Manteia.
RefSeq - XM_015297482
RefSeq - NM_001031382
RefSeq - XM_015297480
RefSeq - XM_015297481
RefSeq Peptide - NP_001026553
swissprot - A0A1D5P975
swissprot - Q5ZJA7
Ensembl - ENSGALG00000014155
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ogdhaENSDARG00000034270Danio rerio
 ogdhbENSDARG00000103428Danio rerio
 OGDHENSG00000105953Homo sapiens
 OgdhENSMUSG00000020456Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OGDHL / oxoglutarate dehydrogenase like / Q9ULD0*ENSGALG0000000226676
DHTKD1 / dehydrogenase E1 and transketolase domain containing 1 / A2ATU0* / Q96HY7* / Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial *ENSGALG0000000367434


Protein motifs (from Interpro)
Interpro ID Name
 IPR001017  Dehydrogenase, E1 component
 IPR005475  Transketolase-like, pyrimidine-binding domain
 IPR011603  2-oxoglutarate dehydrogenase E1 component
 IPR029061  Thiamin diphosphate-binding fold
 IPR031717  Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal
 IPR032106  2-oxoglutarate dehydrogenase E1 component, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0006103 2-oxoglutarate metabolic process IEA
 biological_processGO:0006104 succinyl-CoA metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0021695 cerebellar cortex development IEA
 biological_processGO:0021756 striatum development IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0021794 thalamus development IEA
 biological_processGO:0021860 pyramidal neuron development IEA
 biological_processGO:0022028 tangential migration from the subventricular zone to the olfactory bulb IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0061034 olfactory bulb mitral cell layer development IEA
 biological_processGO:0106077 histone succinylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0045252 oxoglutarate dehydrogenase complex IEA
 molecular_functionGO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity IEA
 molecular_functionGO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEA
 molecular_functionGO:0030976 thiamine pyrophosphate binding IEA
 molecular_functionGO:0034602 oxoglutarate dehydrogenase (NAD+) activity IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Lysine catabolism
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007931 DLD / dihydrolipoamide dehydrogenase / O08749* / P09622* / Dihydrolipoyl dehydrogenase, mitochondrial *  / complex
 ENSGALG00000014155 OGDH / oxoglutarate dehydrogenase / Q02218* / Q60597* / 2-oxoglutarate dehydrogenase, mitochondrial *  / complex






 

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