ENSDARG00000016443


Danio rerio

Features
Gene ID: ENSDARG00000016443
  
Biological name :eif3c
  
Synonyms : eif3c / eukaryotic translation initiation factor 3, subunit C
  
Possible biological names infered from orthology : B5ME19 / EIF3CL / eukaryotic translation initiation factor 3 subunit C like / Q8R1B4 / Q99613
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 3944229
Gene end: 3962372
  
Corresponding Affymetrix probe sets: Dr.20070.1.S1_at (Zebrafish Array)   NM_213463_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000011344
NCBI entrez gene - 334234     See in Manteia.
RefSeq - NM_213463
RefSeq Peptide - NP_998628
swissprot - F1QUG5
ZFIN ID - ZDB-GENE-030131-6166
Ensembl - ENSDARG00000016443
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B5ME19ENSG00000205609Homo sapiens
 EIF3CENSG00000184110Homo sapiens
 Eif3cENSMUSG00000030738Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR008905  Eukaryotic translation initiation factor 3 subunit C, N-terminal domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR027516  Eukaryotic translation initiation factor 3 subunit C


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001732 formation of cytoplasmic translation initiation complex IEA
 biological_processGO:0002183 cytoplasmic translational initiation IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IEA
 cellular_componentGO:0016282 eukaryotic 43S preinitiation complex IEA
 cellular_componentGO:0033290 eukaryotic 48S preinitiation complex IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0031369 translation initiation factor binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism morphology , abnormal
whole organism degenerate , abnormal
whole organism deformed , abnormal
whole organism viability , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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