ENSG00000184110


Homo sapiens

Features
Gene ID: ENSG00000184110
  
Biological name :EIF3C
  
Synonyms : EIF3C / eukaryotic translation initiation factor 3 subunit C / Q99613
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p11.2
Gene start: 28688558
Gene end: 28735730
  
Corresponding Affymetrix probe sets: 200647_x_at (Human Genome U133 Plus 2.0 Array)   210949_s_at (Human Genome U133 Plus 2.0 Array)   215230_x_at (Human Genome U133 Plus 2.0 Array)   236700_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457418
Ensembl peptide - ENSP00000457389
Ensembl peptide - ENSP00000457963
Ensembl peptide - ENSP00000332604
Ensembl peptide - ENSP00000378953
Ensembl peptide - ENSP00000455277
Ensembl peptide - ENSP00000455278
Ensembl peptide - ENSP00000456416
NCBI entrez gene - 8663     See in Manteia.
OMIM - 603916
RefSeq - XM_017023814
RefSeq - NM_001037808
RefSeq - NM_001199142
RefSeq - NM_001267574
RefSeq - NM_001286478
RefSeq - NM_003752
RefSeq Peptide - NP_003743
RefSeq Peptide - NP_001032897
RefSeq Peptide - NP_001186071
RefSeq Peptide - NP_001254503
RefSeq Peptide - NP_001273407
swissprot - H3BPE3
swissprot - Q99613
swissprot - A0A024QYU9
swissprot - H3BPE4
swissprot - H3BTY8
Ensembl - ENSG00000184110
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif3cENSDARG00000016443Danio rerio
 Eif3cENSMUSG00000030738Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
B5ME19 / EIF3CL / eukaryotic translation initiation factor 3 subunit C likeENSG00000205609100


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR008905  Eukaryotic translation initiation factor 3 subunit C, N-terminal domain
 IPR027516  Eukaryotic translation initiation factor 3 subunit C
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001732 formation of cytoplasmic translation initiation complex IEA
 biological_processGO:0002183 cytoplasmic translational initiation IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0045727 positive regulation of translation IPI
 biological_processGO:1902416 positive regulation of mRNA binding IPI
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IDA
 cellular_componentGO:0016282 eukaryotic 43S preinitiation complex IEA
 cellular_componentGO:0033290 eukaryotic 48S preinitiation complex IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003743 translation initiation factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031369 translation initiation factor binding IBA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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