ENSDARG00000016835


Danio rerio

Features
Gene ID: ENSDARG00000016835
  
Biological name :tcirg1a
  
Synonyms : T cell immune regulator 1, ATPase H+ transporting V0 subunit a3a / tcirg1a
  
Possible biological names infered from orthology : Q13488 / T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 / T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 / TCIRG1
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 44870880
Gene end: 44901163
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000114268
Ensembl peptide - ENSDARP00000150591
NCBI entrez gene - 100003139     See in Manteia.
RefSeq - XM_005160272
swissprot - B8A655
ZFIN ID - ZDB-GENE-090311-31
Ensembl - ENSDARG00000016835
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TCIRG1ENSGALG00000036069Gallus gallus
 Q13488ENSG00000110719Homo sapiens
 Tcirg1ENSMUSG00000001750Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tcirg1b / T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b / TCIRG1* / Q13488* / T cell immune regulator 1, ATPase H+ transporting V0 subunit a3* / T cell, immune regulator ...ENSDARG0000010514275
atp6v0a2b / ATPase H+ transporting V0 subunit a2b / P15920* / Q9Y487* / ATP6V0A2* / ATPase H+ transporting V0 subunit a2* / V-type proton ATPase 116 kDa subunit a isoform 2 *ENSDARG0000003556556
atp6v0a2a / ATPase H+ transporting V0 subunit a2a / P15920* / Q9Y487* / ATP6V0A2* / ATPase H+ transporting V0 subunit a2* / V-type proton ATPase 116 kDa subunit a isoform 2 *ENSDARG0000003553855
atp6v0a1b / ATPase H+ transporting V0 subunit a1b / Q9Z1G4* / Q93050* / ATP6V0A1* / ATPase H+ transporting V0 subunit a1* / ATPase, H+ transporting, lysosomal V0 subunit A1*ENSDARG0000001517452
atp6v0a1a / ATPase H+ transporting V0 subunit a1a / Q9Z1G4* / Q93050* / ATP6V0A1* / ATPase H+ transporting V0 subunit a1* / ATPase, H+ transporting, lysosomal V0 subunit A1*ENSDARG0000002084750
si:ch73-173p19.2 / Q920R6* / Q9HBG4* / ATP6V0A4* / ATPase H+ transporting V0 subunit a4* / ATPase, H+ transporting, lysosomal V0 subunit A4*ENSDARG0000010397143


Protein motifs (from Interpro)
Interpro ID Name
 IPR002490  V-type ATPase, V0 complex, 116kDa subunit family
 IPR026028  ATPase, V0 complex, subunit 116kDa, eukaryotic


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007035 vacuolar acidification IBA
 biological_processGO:0015986 ATP synthesis coupled proton transport IBA
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0070072 vacuolar proton-transporting V-type ATPase complex assembly IBA
 cellular_componentGO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016471 vacuolar proton-transporting V-type ATPase complex IBA
 cellular_componentGO:0033179 proton-transporting V-type ATPase, V0 domain IEA
 molecular_functionGO:0015078 proton transmembrane transporter activity IEA
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism IBA
 molecular_functionGO:0051117 ATPase binding IBA


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Neutrophil degranulation
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035565 atp6v0a2b / ATPase H+ transporting V0 subunit a2b / P15920* / Q9Y487* / ATP6V0A2* / ATPase H+ transporting V0 subunit a2* / V-type proton ATPase 116 kDa subunit a isoform 2 *  / complex
 ENSDARG00000035538 atp6v0a2a / ATPase H+ transporting V0 subunit a2a / P15920* / Q9Y487* / ATP6V0A2* / ATPase H+ transporting V0 subunit a2* / V-type proton ATPase 116 kDa subunit a isoform 2 *  / complex






 

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