ENSDARG00000017049


Danio rerio

Features
Gene ID: ENSDARG00000017049
  
Biological name :adsl
  
Synonyms : adenylosuccinate lyase / adsl
  
Possible biological names infered from orthology : P30566 / P54822
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 24207243
Gene end: 24218622
  
Corresponding Affymetrix probe sets: Dr.13359.1.S1_at (Zebrafish Array)   NM_199899_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000022310
Ensembl peptide - ENSDARP00000113091
NCBI entrez gene - 334431     See in Manteia.
RefSeq - NM_199899
RefSeq Peptide - NP_956193
swissprot - F1R293
swissprot - E9QH78
ZFIN ID - ZDB-GENE-030131-6363
Ensembl - ENSDARG00000017049
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADSLENSGALG00000012034Gallus gallus
 ADSLENSG00000239900Homo sapiens
 AdslENSMUSG00000022407Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000362  Fumarate lyase family
 IPR004769  Adenylosuccinate lyase
 IPR008948  L-Aspartase-like
 IPR019468  Adenylosuccinate lyase C-terminal
 IPR020557  Fumarate lyase, conserved site
 IPR022761  Fumarate lyase, N-terminal
 IPR024083  Fumarase/histidase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0006189 "de novo" IMP biosynthetic process IEA
 biological_processGO:0009152 purine ribonucleotide biosynthetic process IEA
 biological_processGO:0044208 "de novo" AMP biosynthetic process IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity IBA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0070626 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity IBA


Pathways (from Reactome)
Pathway description
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000017049 adsl / adenylosuccinate lyase / P30566* / P54822*  / complex






 

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contact: otassy@igbmc.fr