ENSDARG00000017115


Danio rerio

Features
Gene ID: ENSDARG00000017115
  
Biological name :kctd10
  
Synonyms : kctd10 / potassium channel tetramerization domain containing 10
  
Possible biological names infered from orthology : Q9H3F6
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 19436483
Gene end: 19444949
  
Corresponding Affymetrix probe sets: Dr.8455.1.A1_at (Zebrafish Array)   NM_213478_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000122490
Ensembl peptide - ENSDARP00000157459
NCBI entrez gene - 406787     See in Manteia.
RefSeq - NM_213478
RefSeq Peptide - NP_998643
swissprot - Q6P7X5
ZFIN ID - ZDB-GENE-040426-2843
Ensembl - ENSDARG00000017115
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCTD10ENSGALG00000005138Gallus gallus
 KCTD10ENSG00000110906Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tnfaip1 / tumor necrosis factor, alpha-induced protein 1 (endothelial) / O70479* / Q13829* / TNF alpha induced protein 1*ENSDARG0000004156565
kctd13 / A9ULR9 / potassium channel tetramerization domain containing 13 / Q8WZ19* / Q8BGV7* / potassium channel tetramerisation domain containing 13*ENSDARG0000004476961
kctd7 / potassium channel tetramerization domain containing 7 / Q8BJK1* / Q96MP8* / BTB/POZ domain-containing protein KCTD7 *ENSDARG0000006158019
kctd14 / potassium channel tetramerization domain containing 14 / Q9BQ13*ENSDARG0000011024016


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR011333  SKP1/BTB/POZ domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0002040 sprouting angiogenesis IMP
 biological_processGO:0003157 endocardium development IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0033339 pectoral fin development IMP
 biological_processGO:0036302 atrioventricular canal development IMP
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:1900125 regulation of hyaluronan biosynthetic process IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0098811 transcriptional repressor activity, RNA polymerase II activating transcription factor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000114 heart heart unlumenized , abnormal
heart decreased size , abnormal
heart morphology , abnormal
heart tubular , abnormal
Show

 ZFA:0000155 somite somite morphology , abnormal
Show

 ZFA:0001058 caudal fin caudal fin kinked , abnormal
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 ZFA:0001094 whole organism whole organism morphology , abnormal
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 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
trunk decreased size , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin decreased size , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel absent , abnormal
intersegmental vessel sprouting angiogenesis decreased occurrence , abnormal
Show

 ZFA:0001315 atrioventricular canal atrioventricular canal malformed , abnormal
Show

 ZFA:0001318 cardiac jelly cardiac jelly increased thickness , abnormal
Show

 ZFA:0001319 myocardium myocardium decreased size , abnormal
Show

 ZFA:0001320 endocardium endocardium increased distance myocardium , abnormal
endocardium decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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