ENSDARG00000017439


Danio rerio

Features
Gene ID: ENSDARG00000017439
  
Biological name :eif4ba
  
Synonyms : eif4ba / eukaryotic translation initiation factor 4Ba
  
Possible biological names infered from orthology : EIF4B / eukaryotic translation initiation factor 4B / P23588 / Q8BGD9
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 10396842
Gene end: 10453077
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000119691
Ensembl peptide - ENSDARP00000135390
Ensembl peptide - ENSDARP00000112056
Ensembl peptide - ENSDARP00000113681
NCBI entrez gene - 553214     See in Manteia.
RefSeq - XM_005161957
swissprot - A0A0R4IMF6
swissprot - F1QAA4
swissprot - F1QRZ3
swissprot - F1R518
ZFIN ID - ZDB-GENE-060629-1
Ensembl - ENSDARG00000017439
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF4BENSG00000063046Homo sapiens
 Eif4bENSMUSG00000058655Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eif4bb / eukaryotic translation initiation factor 4Bb / EIF4B* / Q8BGD9* / P23588* / eukaryotic translation initiation factor 4B*ENSDARG0000001019464
eif4h / eukaryotic translation initiation factor 4h / Q15056* / Q9WUK2*ENSDARG0000004225216


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR033107  Eukaryotic translation initiation factor 4B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001731 formation of translation preinitiation complex IBA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0097010 eukaryotic translation initiation factor 4F complex assembly IEA
 cellular_componentGO:0005844 polysome IBA
 cellular_componentGO:0016281 eukaryotic translation initiation factor 4F complex IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IBA
 molecular_functionGO:0033592 RNA strand annealing activity IBA
 molecular_functionGO:0034057 RNA strand-exchange activity IBA
 molecular_functionGO:0043024 ribosomal small subunit binding IBA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
mTORC1-mediated signalling
Deadenylation of mRNA
Translation initiation complex formation
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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