ENSMUSG00000058655


Mus musculus

Features
Gene ID: ENSMUSG00000058655
  
Biological name :Eif4b
  
Synonyms : Eif4b / Eukaryotic translation initiation factor 4B / Q8BGD9
  
Possible biological names infered from orthology : P23588
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: F2
Gene start: 102073773
Gene end: 102097173
  
Corresponding Affymetrix probe sets: 10427083 (MoGene1.0st)   1426378_at (Mouse Genome 430 2.0 Array)   1426379_at (Mouse Genome 430 2.0 Array)   1426380_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000155206
Ensembl peptide - ENSMUSP00000127774
NCBI entrez gene - 75705     See in Manteia.
MGI - MGI:95304
RefSeq - NM_145625
RefSeq Peptide - NP_663600
swissprot - B2RWE8
swissprot - Q8BGD9
Ensembl - ENSMUSG00000058655
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif4baENSDARG00000017439Danio rerio
 eif4bbENSDARG00000010194Danio rerio
 EIF4BENSG00000063046Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Eif4h / Q9WUK2 / Eukaryotic translation initiation factor 4H / Q15056*ENSMUSG0000004073118


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR033107  Eukaryotic translation initiation factor 4B
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001731 formation of translation preinitiation complex IBA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0097010 eukaryotic translation initiation factor 4F complex assembly IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005844 polysome IBA
 cellular_componentGO:0016281 eukaryotic translation initiation factor 4F complex IBA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IBA
 molecular_functionGO:0033592 RNA strand annealing activity IBA
 molecular_functionGO:0034057 RNA strand-exchange activity IBA
 molecular_functionGO:0043024 ribosomal small subunit binding IBA


Pathways (from Reactome)
Pathway description
mTORC1-mediated signalling
Deadenylation of mRNA
Ribosomal scanning and start codon recognition


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020516 Q8BSK8 / Rps6kb1 / ribosomal protein S6 kinase, polypeptide 1 / P23443* / ribosomal protein S6 kinase B1*  / reaction






 

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