ENSDARG00000017772


Danio rerio

Features
Gene ID: ENSDARG00000017772
  
Biological name :mdh1aa
  
Synonyms : malate dehydrogenase 1Aa, NAD (soluble) / mdh1aa
  
Possible biological names infered from orthology : malate dehydrogenase 1 / Malate dehydrogenase, cytoplasmic / MDH1 / P14152 / P40925
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 50968908
Gene end: 50990889
  
Corresponding Affymetrix probe sets: Dr.4960.1.S1_at (Zebrafish Array)   Dr.4960.1.S1_a_at (Zebrafish Array)   NM_199947_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000120477
Ensembl peptide - ENSDARP00000125163
Ensembl peptide - ENSDARP00000015862
Ensembl peptide - ENSDARP00000023121
Ensembl peptide - ENSDARP00000116018
NCBI entrez gene - 399662     See in Manteia.
RefSeq - NM_001309523
RefSeq - NM_001316925
RefSeq - NM_199947
RefSeq Peptide - NP_001296452
RefSeq Peptide - NP_001303854
RefSeq Peptide - NP_956241
swissprot - H0WE86
swissprot - Q801E6
swissprot - B8JMY8
swissprot - Q7T3D9
swissprot - B8JMZ0
ZFIN ID - ZDB-GENE-040204-1
Ensembl - ENSDARG00000017772
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MDH1ENSGALG00000008858Gallus gallus
 MDH1ENSG00000014641Homo sapiens
 Mdh1ENSMUSG00000020321Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mdh1ab / malate dehydrogenase 1Ab, NAD (soluble) / MDH1* / P14152* / P40925* / malate dehydrogenase 1* / Malate dehydrogenase, cytoplasmic *ENSDARG0000010384966
mdh1b / malate dehydrogenase 1B, NAD (soluble) / Q5F204* / Q5I0G3* / malate dehydrogenase 1B* / Putative malate dehydrogenase 1B *ENSDARG0000001800826


Protein motifs (from Interpro)
Interpro ID Name
 IPR001236  Lactate/malate dehydrogenase, N-terminal
 IPR001252  Malate dehydrogenase, active site
 IPR001557  L-lactate/malate dehydrogenase
 IPR010945  Malate dehydrogenase, type 2
 IPR011274  Malate dehydrogenase, NAD-dependent, cytosolic
 IPR015955  Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
 IPR016040  NAD(P)-binding domain
 IPR022383  Lactate/malate dehydrogenase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0006107 oxaloacetate metabolic process IBA
 biological_processGO:0006108 malate metabolic process IEA
 biological_processGO:0006734 NADH metabolic process IBA
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016615 malate dehydrogenase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0030060 L-malate dehydrogenase activity IEA


Pathways (from Reactome)
Pathway description
Gluconeogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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