ENSDARG00000018953


Danio rerio

Features
Gene ID: ENSDARG00000018953
  
Biological name :gclm
  
Synonyms : gclm / glutamate-cysteine ligase, modifier subunit
  
Possible biological names infered from orthology : Glutamate--cysteine ligase regulatory subunit / O09172 / P48507
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 15269423
Gene end: 15277252
  
Corresponding Affymetrix probe sets: Dr.11547.1.S1_at (Zebrafish Array)   NM_199845_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000023515
NCBI entrez gene - 333974     See in Manteia.
RefSeq - NM_199845
RefSeq - XM_009303802
RefSeq Peptide - NP_956139
swissprot - A8WHP4
ZFIN ID - ZDB-GENE-030131-5906
Ensembl - ENSDARG00000018953
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GCLMENSG00000023909Homo sapiens
 GclmENSMUSG00000028124Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR023210  NADP-dependent oxidoreductase domain
 IPR032963  Glutamate--cysteine ligase regulatory subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006750 glutathione biosynthetic process IBA
 biological_processGO:0035229 positive regulation of glutamate-cysteine ligase activity IBA
 cellular_componentGO:0017109 glutamate-cysteine ligase complex IBA
 molecular_functionGO:0030234 enzyme regulator activity IBA
 molecular_functionGO:0035226 glutamate-cysteine ligase catalytic subunit binding IEA


Pathways (from Reactome)
Pathway description
Glutathione synthesis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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