ENSDARG00000019772


Danio rerio

Features
Gene ID: ENSDARG00000019772
  
Biological name :si:ch1073-280e3.1
  
Synonyms : si:ch1073-280e3.1
  
Possible biological names infered from orthology : C2 / complement C2 / Complement C2 Complement C2b fragment Complement C2a fragment / P06681 / P21180
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 478524
Gene end: 496549
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000015169
NCBI entrez gene - 563828     See in Manteia.
swissprot - F1QJB3
ZFIN ID - ZDB-GENE-110411-261
Ensembl - ENSDARG00000019772
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 C2ENSGALG00000035721Gallus gallus
 C2ENSG00000166278Homo sapiens
 C2ENSMUSG00000024371Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cfbl / complement factor b-like / CFB* / P04186* / P00751* / Gm20547* / AL645922.1* / complement factor B* / Complement factor B Complement factor B Ba fragment Complement factor B Bb fragment*ENSDARG0000009073026
cfb / complement factor B / P04186* / P00751* / Gm20547* / AL645922.1* / Complement factor B Complement factor B Ba fragment Complement factor B Bb fragment*ENSDARG0000005527826
bfb / complement component bfb / CFB* / P04186* / P00751* / Gm20547* / AL645922.1* / complement factor B* / Complement factor B Complement factor B Ba fragment Complement factor B Bb fragment*ENSDARG0000000561615


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR002035  von Willebrand factor, type A
 IPR009003  Peptidase S1, PA clan
 IPR011360  Complement B/C2
 IPR018114  Serine proteases, trypsin family, histidine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006956 complement activation IEA
 biological_processGO:0006958 complement activation, classical pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Initial triggering of complement
Activation of C3 and C5
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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