ENSDARG00000005616


Danio rerio

Features
Gene ID: ENSDARG00000005616
  
Biological name :bfb
  
Synonyms : bfb / complement component bfb
  
Possible biological names infered from orthology : AL645922.1 / CFB / complement factor B / Complement factor B Complement factor B Ba fragment Complement factor B Bb fragment / Gm20547 / P00751 / P04186
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 27437867
Gene end: 27443995
  
Corresponding Affymetrix probe sets: Dr.5741.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000023622
NCBI entrez gene - 30489     See in Manteia.
RefSeq - XM_021468750
RefSeq - NM_131241
RefSeq Peptide - NP_571316
swissprot - Q6DHC4
ZFIN ID - ZDB-GENE-990415-34
Ensembl - ENSDARG00000005616
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AL645922.1ENSG00000244255Homo sapiens
 CFBENSG00000243649Homo sapiens
 CfbENSMUSG00000090231Mus musculus
 Gm20547ENSMUSG00000092511Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cfb / complement factor B / P04186* / P00751* / Gm20547* / AL645922.1* / Complement factor B Complement factor B Ba fragment Complement factor B Bb fragment*ENSDARG0000005527877
cfbl / complement factor b-like / CFB* / P04186* / P00751* / Gm20547* / AL645922.1* / complement factor B* / Complement factor B Complement factor B Ba fragment Complement factor B Bb fragment*ENSDARG0000009073054
si:ch1073-280e3.1 / C2* / P06681* / complement C2*ENSDARG0000001977227


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR002035  von Willebrand factor, type A


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
Alternative complement activation
Activation of C3 and C5
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000021004 c5 / complement component 5 / P01031* / complement C5*  / reaction
 ENSDARG00000039579 cfd / complement factor D (adipsin) / P00746* / P03953* / complement factor D*  / reaction
 ENSDARG00000094451 cfp / complement factor properdin / P11680* / P27918*  / reaction / complex
 ENSDARG00000078114 si:ch73-237c6.1 / CFP* / P11680* / P27918* / complement factor properdin*  / reaction / complex






 

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