ENSMUSG00000092511


Mus musculus

Features
Gene ID: ENSMUSG00000092511
  
Biological name :Gm20547
  
Synonyms : Gm20547
  
Possible biological names infered from orthology : AL645922.1 / CFB / complement factor B / P00751
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: B1
Gene start: 34856412
Gene end: 34882042
  
Corresponding Affymetrix probe sets: 10450325 (MoGene1.0st)   10450344 (MoGene1.0st)   1417314_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117677
Ensembl peptide - ENSMUSP00000120864
MGI - MGI:5142012
swissprot - B8JJN0
swissprot - F6VQX8
Ensembl - ENSMUSG00000092511
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bfbENSDARG00000005616Danio rerio
 cfbENSDARG00000055278Danio rerio
 cfblENSDARG00000090730Danio rerio
 AL645922.1ENSG00000244255Homo sapiens
 CFBENSG00000243649Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cfb / P04186 / Complement factor B Complement factor B Ba fragment Complement factor B Bb fragment / P00751* / AL645922.1* / complement factor B*ENSMUSG0000009023158
C2 / P21180 / Complement C2 Complement C2b fragment Complement C2a fragment / P06681* / complement C2*ENSMUSG0000002437123


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR002035  von Willebrand factor, type A
 IPR009003  Peptidase S1, PA clan
 IPR011360  Complement B/C2
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR028341  Complement factor B
 IPR033116  Serine proteases, trypsin family, serine active site
 IPR035976  Sushi/SCR/CCP superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006956 complement activation IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Alternative complement activation
Activation of C3 and C5
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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