ENSDARG00000019949


Danio rerio

Features
Gene ID: ENSDARG00000019949
  
Biological name :serpinh1b
  
Synonyms : serpinh1b / serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
  
Possible biological names infered from orthology : P19324 / P50454 / serpin family H member 1 / Serpin H1 / SERPINH1
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 29382454
Gene end: 29388012
  
Corresponding Affymetrix probe sets: Dr.106.1.S1_at (Zebrafish Array)   NM_131204_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000097918
Ensembl peptide - ENSDARP00000114717
Ensembl peptide - ENSDARP00000037780
NCBI entrez gene - 30449     See in Manteia.
RefSeq - NM_131204
RefSeq Peptide - NP_001296752
RefSeq Peptide - NP_571279
swissprot - F1QQ04
swissprot - E9QEB4
swissprot - F1R7F7
ZFIN ID - ZDB-GENE-990415-93
Ensembl - ENSDARG00000019949
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P13731ENSGALG00000011214Gallus gallus
 P50454ENSG00000149257Homo sapiens
 P19324ENSMUSG00000070436Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
serpinh1a / serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a / P50454* / P19324* / SERPINH1* / Serpin H1 * / serpin family H member 1*ENSDARG0000007595476
serpinh2 / serine (or cysteine) peptidase inhibitor, clade H, member 2ENSDARG0000003644531
serpini1 / serpin peptidase inhibitor, clade I (neuroserpin), member 1 / O35684* / Q99574* / serpin family I member 1* / serine (or cysteine) peptidase inhibitor, clade I, member 1*ENSDARG0000003416825
serpinc1 / serpin peptidase inhibitor, clade C (antithrombin), member 1 / P01008* / P32261* / serpin family C member 1* / serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1*ENSDARG0000004268423
serpine2 / serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 / P07093* / serpin family E member 2*ENSDARG0000002935323
B0UYL8 / serpine3 / serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 / A8MV23* / serpin family E member 3*ENSDARG0000005710821
serpine1 / serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 / P05121* / serpin family E member 1* / serine (or cysteine) peptidase inhibitor, cl...ENSDARG0000005679521


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR033547  Serpin H1
 IPR033830  Serpin H1 inhibitory domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030199 collagen fibril organization IBA
 biological_processGO:0031101 fin regeneration IMP
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0005518 collagen binding IEA


Pathways (from Reactome)
Pathway description
Collagen biosynthesis and modifying enzymes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001269 regenerating fin regenerating fin decreased length , abnormal
regenerating fin decreased amount , abnormal
regenerating fin cell proliferation decreased occurrence , abnormal
regenerating fin bone element decreased length , abnormal
regenerating fin actinotrichium morphology , abnormal
regenerating fin actinotrichium decreased size , abnormal
regenerating fin lepidotrichium segment decreased length , abnormal
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 ZFA:0005634 lepidotrichium joint lepidotrichium joint fin regeneration premature , abnormal
lepidotrichium joint fin morphogenesis premature , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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