ENSDARG00000020242


Danio rerio

Features
Gene ID: ENSDARG00000020242
  
Biological name :fermt2
  
Synonyms : F1Q8X5 / fermitin family member 2 / fermt2
  
Possible biological names infered from orthology : Fermitin family homolog 2 / Q8CIB5 / Q96AC1
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 50701748
Gene end: 50787754
  
Corresponding Affymetrix probe sets: Dr.21282.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000049463
Ensembl peptide - ENSDARP00000150985
Ensembl peptide - ENSDARP00000156911
NCBI entrez gene - 553051     See in Manteia.
RefSeq - NM_001256215
RefSeq Peptide - NP_001243144
swissprot - F1Q8X5
ZFIN ID - ZDB-GENE-050506-132
Ensembl - ENSDARG00000020242
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FERMT2ENSGALG00000012425Gallus gallus
 FERMT2ENSG00000073712Homo sapiens
 Fermt2ENSMUSG00000037712Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fermt1 / fermitin family member 1 / P59113* / Q9BQL6* / Fermitin family homolog 1 *ENSDARG0000005265259
im:7154036 / FERMT3 (1 of many) / FERMT3* / Q86UX7* / Q8K1B8* / fermitin family member 3* / Fermitin family homolog 3 *ENSDARG0000007926750
fermt3b / fermitin family member 3b / Q8K1B8* / FERMT3* / Q86UX7* / fermitin family member 3* / Fermitin family homolog 3 *ENSDARG0000003093848


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0007010 cytoskeleton organization IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016477 cell migration IGI
 biological_processGO:0055008 cardiac muscle tissue morphogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0014704 intercalated disc IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031258 lamellipodium membrane IEA
 cellular_componentGO:0031674 I band IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Cell-extracellular matrix interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle malformed , abnormal
Show

 ZFA:0000009 cardiac ventricle cardiac ventricle decreased size , abnormal
cardiac ventricle dilated , abnormal
cardiac ventricle decreased contractility , abnormal
Show

 ZFA:0000012 central nervous system central nervous system morphology , abnormal
Show

 ZFA:0000023 forerunner cell group forerunner cell group disorganized , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye morphology , abnormal
Show

 ZFA:0000114 heart heart morphology , abnormal
Show

 ZFA:0000471 atrium atrium dilated , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
whole organism paralysed , abnormal
Show

 ZFA:0001115 trunk trunk bent , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel decreased length , abnormal
intersegmental vessel decreased thickness , abnormal
Show

 ZFA:0005024 trunk vasculature trunk vasculature malformed , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel morphology , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell vacuolated , abnormal
skeletal muscle cell myofibril disorganized , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell intercalated disc decreased thickness , abnormal
cardiac muscle cell intercalated disc decreased amount , abnormal
cardiac muscle cell sarcomere mislocalised , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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