ENSG00000073712


Homo sapiens

Features
Gene ID: ENSG00000073712
  
Biological name :FERMT2
  
Synonyms : fermitin family member 2 / FERMT2 / Q96AC1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q22.1
Gene start: 52857268
Gene end: 52952435
  
Corresponding Affymetrix probe sets: 209209_s_at (Human Genome U133 Plus 2.0 Array)   209210_s_at (Human Genome U133 Plus 2.0 Array)   214212_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451268
Ensembl peptide - ENSP00000451134
Ensembl peptide - ENSP00000452472
Ensembl peptide - ENSP00000489609
Ensembl peptide - ENSP00000340391
Ensembl peptide - ENSP00000342858
Ensembl peptide - ENSP00000378993
Ensembl peptide - ENSP00000382243
Ensembl peptide - ENSP00000450506
Ensembl peptide - ENSP00000450741
Ensembl peptide - ENSP00000451084
Ensembl peptide - ENSP00000451085
NCBI entrez gene - 10979     See in Manteia.
OMIM - 607746
RefSeq - XM_006720010
RefSeq - NM_001134999
RefSeq - NM_001135000
RefSeq - NM_006832
RefSeq - XM_005267285
RefSeq - XM_006720008
RefSeq - XM_006720009
RefSeq Peptide - NP_006823
RefSeq Peptide - NP_001128471
RefSeq Peptide - NP_001128472
swissprot - A0A0U1RRM8
swissprot - G3V281
swissprot - G3V379
swissprot - G3V3J0
swissprot - G3V5R2
swissprot - H0YJB6
swissprot - H0YJ34
swissprot - Q96AC1
swissprot - A0A024R687
Ensembl - ENSG00000073712
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F1Q8X5ENSDARG00000020242Danio rerio
 FERMT2ENSGALG00000012425Gallus gallus
 Fermt2ENSMUSG00000037712Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FERMT1 / Q9BQL6 / fermitin family member 1ENSG0000010131162
FERMT3 / Q86UX7 / fermitin family member 3ENSG0000014978151


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR035963  FERM superfamily, second domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0007229 integrin-mediated signaling pathway IMP
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0016055 Wnt signaling pathway IMP
 biological_processGO:0033622 integrin activation IEA
 biological_processGO:0034329 cell junction assembly TAS
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IEA
 biological_processGO:0048041 focal adhesion assembly IEA
 biological_processGO:0072657 protein localization to membrane IEA
 cellular_componentGO:0001725 stress fiber IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0031258 lamellipodium membrane IEA
 cellular_componentGO:0031674 I band IEA
 cellular_componentGO:0031941 filamentous actin IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IDA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Cell-extracellular matrix interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000162458 FBLIM1 / Q8WUP2 / filamin binding LIM protein 1  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr