ENSG00000162458


Homo sapiens

Features
Gene ID: ENSG00000162458
  
Biological name :FBLIM1
  
Synonyms : FBLIM1 / filamin binding LIM protein 1 / Q8WUP2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.21
Gene start: 15756607
Gene end: 15786594
  
Corresponding Affymetrix probe sets: 1554795_a_at (Human Genome U133 Plus 2.0 Array)   1555480_a_at (Human Genome U133 Plus 2.0 Array)   1555483_x_at (Human Genome U133 Plus 2.0 Array)   225258_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402401
Ensembl peptide - ENSP00000387595
Ensembl peptide - ENSP00000416387
Ensembl peptide - ENSP00000427052
Ensembl peptide - ENSP00000424920
Ensembl peptide - ENSP00000423471
Ensembl peptide - ENSP00000422862
Ensembl peptide - ENSP00000422075
Ensembl peptide - ENSP00000421885
Ensembl peptide - ENSP00000421764
Ensembl peptide - ENSP00000364920
Ensembl peptide - ENSP00000364921
Ensembl peptide - ENSP00000364926
NCBI entrez gene - 54751     See in Manteia.
OMIM - 607747
RefSeq - XM_017001526
RefSeq - XM_005245903
RefSeq - XM_005245909
RefSeq - XM_006710704
RefSeq - XM_006710705
RefSeq - XM_011541616
RefSeq - XM_011541617
RefSeq - XM_011541618
RefSeq - XM_017001519
RefSeq - XM_017001520
RefSeq - XM_017001521
RefSeq - XM_017001522
RefSeq - XM_017001523
RefSeq - XM_017001524
RefSeq - XM_017001525
RefSeq - NM_001024215
RefSeq - NM_001024216
RefSeq - NM_001350151
RefSeq - NM_017556
RefSeq - XM_005245900
RefSeq - XM_005245901
RefSeq - XM_005245902
RefSeq Peptide - NP_001337080
RefSeq Peptide - NP_060026
RefSeq Peptide - NP_001019386
RefSeq Peptide - NP_001019387
swissprot - D6RAI6
swissprot - D6RA19
swissprot - D6R9V9
swissprot - E7EWE8
swissprot - Q5VVD3
swissprot - Q8WUP2
swissprot - D6R9I4
swissprot - E7EPI5
swissprot - E7EN81
swissprot - D6RAI8
Ensembl - ENSG00000162458
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fblim1ENSDARG00000071558Danio rerio
 FBLIM1ENSGALG00000003636Gallus gallus
 Fblim1ENSMUSG00000006219Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZYX / zyxin / Q15942ENSG0000015984030
TRIP6 / Q15654 / thyroid hormone receptor interactor 6ENSG0000008707725
LPP / Q93052 / LIM domain containing preferred translocation partner in lipomaENSG0000014501225
LIMD1 / Q9UGP4 / LIM domains containing 1ENSG0000014479124
AJUBA / Q96IF1 / ajuba LIM proteinENSG0000012947420
WTIP / A6NIX2 / WT1 interacting proteinENSG0000014227918
ABLIM1 / O14639 / actin binding LIM protein 1ENSG0000009920413
ABLIM2 / Q6H8Q1 / actin binding LIM protein family member 2ENSG0000016399513
ABLIM3 / O94929 / actin binding LIM protein family member 3ENSG0000017321012
DMTN / Q08495 / dematin actin binding proteinENSG000001588561


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0033623 regulation of integrin activation IMP
 biological_processGO:0034329 cell junction assembly TAS
 biological_processGO:0098609 cell-cell adhesion IMP
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0001725 stress fiber IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031005 filamin binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cell-extracellular matrix interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000125753 VASP / P50552 / vasodilator stimulated phosphoprotein  / reaction / complex
 ENSG00000073712 FERMT2 / Q96AC1 / fermitin family member 2  / complex / reaction
 ENSG00000128591 FLNC / Q14315 / filamin C  / complex / reaction
 ENSG00000184009 ACTG1 / P63261 / actin gamma 1  / complex / reaction
 ENSG00000075624 ACTB / P60709 / actin beta  / reaction / complex
 ENSG00000196924 FLNA / P21333 / filamin A  / reaction / complex






 

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