ENSG00000173210


Homo sapiens

Features
Gene ID: ENSG00000173210
  
Biological name :ABLIM3
  
Synonyms : ABLIM3 / actin binding LIM protein family member 3 / O94929
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q32
Gene start: 149141483
Gene end: 149260542
  
Corresponding Affymetrix probe sets: 205730_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421002
Ensembl peptide - ENSP00000420855
Ensembl peptide - ENSP00000421183
Ensembl peptide - ENSP00000430150
Ensembl peptide - ENSP00000425394
Ensembl peptide - ENSP00000310309
Ensembl peptide - ENSP00000315841
Ensembl peptide - ENSP00000348938
NCBI entrez gene - 22885     See in Manteia.
OMIM - 611305
RefSeq - XM_017009238
RefSeq - NM_001301015
RefSeq - NM_001301018
RefSeq - NM_001301027
RefSeq - NM_001301028
RefSeq - NM_001345859
RefSeq - NM_014945
RefSeq - XM_005268392
RefSeq - XM_005268393
RefSeq - XM_005268394
RefSeq - XM_005268395
RefSeq - XM_005268396
RefSeq Peptide - NP_001287956
RefSeq Peptide - NP_001332790
RefSeq Peptide - NP_055760
RefSeq Peptide - NP_001287944
RefSeq Peptide - NP_001287947
RefSeq Peptide - NP_001287957
RefSeq Peptide - NP_001332788
swissprot - A0A0C4DGA7
swissprot - D6RHE7
swissprot - O94929
swissprot - A0A0A0MRD5
Ensembl - ENSG00000173210
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ablim3ENSDARG00000088168Danio rerio
 ABLIM3ENSGALG00000002790Gallus gallus
 Ablim3ENSMUSG00000032735Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABLIM1 / O14639 / actin binding LIM protein 1ENSG0000009920454
ABLIM2 / Q6H8Q1 / actin binding LIM protein family member 2ENSG0000016399548
DMTN / Q08495 / dematin actin binding proteinENSG0000015885621
ZYX / zyxin / Q15942ENSG0000015984012
LPP / Q93052 / LIM domain containing preferred translocation partner in lipomaENSG0000014501211
TRIP6 / Q15654 / thyroid hormone receptor interactor 6ENSG0000008707711
LIMD1 / Q9UGP4 / LIM domains containing 1ENSG0000014479110
AJUBA / Q96IF1 / ajuba LIM proteinENSG000001294748
WTIP / A6NIX2 / WT1 interacting proteinENSG000001422798
FBLIM1 / Q8WUP2 / filamin binding LIM protein 1ENSG000001624586


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type
 IPR003128  Villin headpiece
 IPR028449  Actin-binding LIM protein 3
 IPR032402  Putative adherens-junction anchoring domain
 IPR036886  Villin headpiece domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0030032 lamellipodium assembly IMP
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0001725 stress fiber IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030027 lamellipodium IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
DCC mediated attractive signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000065320 NTN1 / O95631 / netrin 1  / complex / reaction
 ENSG00000010810 FYN / P06241 / FYN proto-oncogene, Src family tyrosine kinase  / reaction / complex
 ENSG00000158092 NCK1 / P16333 / NCK adaptor protein 1  / reaction / complex
 ENSG00000150760 DOCK1 / Q14185 / dedicator of cytokinesis 1  / complex / reaction
 ENSG00000187323 DCC / P43146 / DCC netrin 1 receptor  / complex / reaction
 ENSG00000038382 TRIO / O75962 / trio Rho guanine nucleotide exchange factor  / reaction / complex
 ENSG00000169398 PTK2 / Q05397 / protein tyrosine kinase 2  / reaction / complex
 ENSG00000136238 RAC1 / P63000 / Rac family small GTPase 1  / complex / reaction
 ENSG00000197122 SRC / P12931 / SRC proto-oncogene, non-receptor tyrosine kinase  / complex / reaction






 

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