ENSG00000142279


Homo sapiens

Features
Gene ID: ENSG00000142279
  
Biological name :WTIP
  
Synonyms : A6NIX2 / WT1 interacting protein / WTIP
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.11
Gene start: 34481638
Gene end: 34512304
  
Corresponding Affymetrix probe sets: 227411_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466953
Ensembl peptide - ENSP00000465683
NCBI entrez gene - 126374     See in Manteia.
OMIM - 614790
RefSeq - XM_011526453
RefSeq - NM_001080436
RefSeq - XM_006723014
RefSeq - XM_011526452
RefSeq Peptide - NP_001073905
swissprot - K7EKM1
swissprot - A6NIX2
Ensembl - ENSG00000142279
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wtipENSDARG00000103607Danio rerio
 WTIPENSGALG00000025864Gallus gallus
 WtipENSMUSG00000036459Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LIMD1 / Q9UGP4 / LIM domains containing 1ENSG0000014479149
AJUBA / Q96IF1 / ajuba LIM proteinENSG0000012947444
ZYX / zyxin / Q15942ENSG0000015984030
LPP / Q93052 / LIM domain containing preferred translocation partner in lipomaENSG0000014501230
TRIP6 / Q15654 / thyroid hormone receptor interactor 6ENSG0000008707725
ABLIM1 / O14639 / actin binding LIM protein 1ENSG0000009920417
FBLIM1 / Q8WUP2 / filamin binding LIM protein 1ENSG0000016245816
ABLIM2 / Q6H8Q1 / actin binding LIM protein family member 2ENSG0000016399514
ABLIM3 / O94929 / actin binding LIM protein family member 3ENSG0000017321013
DMTN / Q08495 / dematin actin binding proteinENSG000001588565


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0007010 cytoskeleton organization IMP
 biological_processGO:0022604 regulation of cell morphogenesis IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0035195 gene silencing by miRNA IMP
 biological_processGO:0035331 negative regulation of hippo signaling IDA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 biological_processGO:2000637 positive regulation of gene silencing by miRNA IMP
 cellular_componentGO:0000932 P-body IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005667 transcription factor complex IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005911 cell-cell junction IBA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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