ENSMUSG00000036459


Mus musculus

Features
Gene ID: ENSMUSG00000036459
  
Biological name :Wtip
  
Synonyms : Q7TQJ8 / WT1-interacting protein / Wtip
  
Possible biological names infered from orthology : A6NIX2
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B1
Gene start: 34109543
Gene end: 34133268
  
Corresponding Affymetrix probe sets: 10562323 (MoGene1.0st)   1433651_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146103
Ensembl peptide - ENSMUSP00000047623
NCBI entrez gene - 101543     See in Manteia.
MGI - MGI:2141920
RefSeq - NM_207212
RefSeq - XM_017321909
RefSeq Peptide - NP_997095
swissprot - A0A0U1RPS6
swissprot - Q7TQJ8
Ensembl - ENSMUSG00000036459
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wtipENSDARG00000103607Danio rerio
 WTIPENSGALG00000025864Gallus gallus
 WTIPENSG00000142279Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Limd1 / Q9QXD8 / LIM domain-containing protein 1 / Q9UGP4* / LIM domains containing 1*ENSMUSG0000002523949
Ajuba / Q91XC0 / LIM domain-containing protein ajuba / Q96IF1* / ajuba LIM protein*ENSMUSG0000002217847
Lpp / Q8BFW7 / Lipoma-preferred partner homolog / Q93052* / LIM domain containing preferred translocation partner in lipoma*ENSMUSG0000003330631
Zyx / zyxin / Q62523 / Q15942*ENSMUSG0000002986029
Trip6 / Q9Z1Y4 / thyroid hormone receptor interactor 6 / Q15654*ENSMUSG0000002334828
Fblim1 / Q71FD7 / Filamin-binding LIM protein 1 / Q8WUP2*ENSMUSG0000000621921
Ablim1 / Q8K4G5 / actin-binding LIM protein 1 / O14639*ENSMUSG0000002508518
Ablim2 / Q8BL65 / actin-binding LIM protein 2 / Q6H8Q1* / actin binding LIM protein family member 2*ENSMUSG0000002909515
Ablim3 / Q69ZX8 / actin binding LIM protein family, member 3 / O94929*ENSMUSG0000003273514
Dmtn / Q9WV69 / Dematin / Q08495* / dematin actin binding protein*ENSMUSG000000220996


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0022604 regulation of cell morphogenesis IEA
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0035195 gene silencing by miRNA IEA
 biological_processGO:0035329 hippo signaling IBA
 biological_processGO:0035331 negative regulation of hippo signaling IEA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 biological_processGO:2000637 positive regulation of gene silencing by miRNA IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005667 transcription factor complex IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IBA
 cellular_componentGO:0005912 adherens junction IBA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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